{"id":4817,"date":"2025-03-21T14:09:26","date_gmt":"2025-03-21T06:09:26","guid":{"rendered":"https:\/\/collagensei.com\/?page_id=4817"},"modified":"2026-10-29T17:21:50","modified_gmt":"2026-10-29T09:21:50","slug":"glcnac","status":"publish","type":"page","link":"https:\/\/collagensei.com\/de\/joint-health-ingredients\/glcnac\/","title":{"rendered":"GlcNAc"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"4817\" class=\"elementor elementor-4817\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-187a92c e-con-full e-flex e-con e-parent\" data-id=\"187a92c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6977e16 elementor-widget elementor-widget-html\" data-id=\"6977e16\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<style>\n.gensei-glcnac-page{\n  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.g-inquiry-step>span{display:flex;width:34px;height:34px;align-items:center;justify-content:center;border-radius:50%;background:var(--g-blue-soft);color:var(--g-blue-dark);font-size:11px;font-weight:800}\n.gensei-glcnac-page .g-inquiry-step h3{margin:0 0 4px;color:var(--g-blue-dark);font-size:16px}.gensei-glcnac-page .g-inquiry-step p{margin:0;color:var(--g-muted);font-size:13.5px;line-height:1.58}\n.gensei-glcnac-page .g-btn{text-decoration:underline!important;text-decoration-thickness:1px!important;text-underline-offset:3px!important}\n.gensei-glcnac-page .g-btn:hover{text-decoration:underline!important}\n@media(max-width:1100px){\n .gensei-glcnac-page .g-facts{grid-template-columns:repeat(3,minmax(0,1fr))}\n .gensei-glcnac-page .g-study-grid{grid-template-columns:1fr}\n}\n@media(max-width:700px){\n .gensei-glcnac-page .g-facts,.gensei-glcnac-page .g-app-grid,.gensei-glcnac-page .g-source-grid,.gensei-glcnac-page .g-compare-grid,.gensei-glcnac-page .g-support-grid{grid-template-columns:1fr}\n}\n<\/style>\n<div class=\"gensei-glcnac-page\">\n<section class=\"g-hero\">\n<div class=\"g-wrap g-hero-grid\">\n<div>\n<p class=\"g-eyebrow\">Joint Health Ingredient<\/p>\n<h1>N-Acetyl Glucosamine Powder Supplier<\/h1>\n<p class=\"g-lead\">N-Acetyl-D-Glucosamine (GlcNAc \/ NAG) powder for joint-health and specialty supplement formulations. Gensei supplies N-acetyl glucosamine for commercial ingredient sourcing, with product identity and technical information available for project discussions.<\/p>\n<div class=\"g-actions\">\n<a class=\"g-btn\" href=\"#glcnac-inquiry\">Request a Quote<\/a>\n<\/div>\n<\/div>\n<div aria-label=\"GlcNAc product image\" class=\"g-image-card\">\n<img alt=\"N-Acetyl Glucosamine powder GlcNAc NAG ingredient\" decoding=\"async\" loading=\"eager\" src=\"https:\/\/collagensei.com\/wp-content\/uploads\/2026\/10\/GlcNAc.webp\"\/>\n<\/div>\n<\/div>\n<\/section><section class=\"g-section\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Ingredient Identity<\/p>\n<h2>N-Acetyl-D-Glucosamine Product Details<\/h2>\n<p>Chemical identity and common naming used for GlcNAc \/ NAG.<\/p>\n<\/div>\n<div class=\"g-facts\">\n<div class=\"g-fact\">\n<span>CAS No.<\/span>\n<strong>7512-17-6<\/strong>\n<\/div>\n<div class=\"g-fact\">\n<span>Molecular Formula<\/span>\n<strong>C\u2088H\u2081\u2085NO\u2086<\/strong>\n<\/div>\n<div class=\"g-fact\">\n<span>Molecular Weight<\/span>\n<strong>221.21 g\/mol<\/strong>\n<\/div>\n<div class=\"g-fact\">\n<span>Common Names<\/span>\n<strong>GlcNAc \/ NAG<\/strong>\n<\/div>\n<div class=\"g-fact\">\n<span>Chemical Name<\/span>\n<strong>N-Acetyl-D-Glucosamine<\/strong>\n<\/div>\n<\/div>\n<\/div>\n<\/section><section class=\"g-section g-section-soft\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Ingredient Comparison<\/p>\n<h2>GlcNAc, Glucosamine HCl &amp; Glucosamine Sulfate<\/h2>\n<p>These are distinct glucosamine forms and should be identified by the exact ingredient specified in the finished formula.<\/p>\n<\/div>\n<div class=\"g-table-wrap\">\n<table>\n<thead>\n<tr>\n<th>Attribute<\/th>\n<th>GlcNAc \/ NAG<\/th>\n<th>Glucosamine HCl<\/th>\n<th>Glucosamine Sulfate<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Chemical form<\/td>\n<td>N-Acetyl-D-Glucosamine<\/td>\n<td>Glucosamine hydrochloride<\/td>\n<td>Glucosamine sulfate<\/td>\n<\/tr>\n<tr>\n<td>Specification focus<\/td>\n<td>Identity, assay, source, particle size and supporting documents<\/td>\n<td>Salt identity, assay and applicable specification<\/td>\n<td>Sulfate form, assay and applicable specification<\/td>\n<\/tr>\n<tr>\n<td>Formula use<\/td>\n<td>Select when the formula calls for GlcNAc<\/td>\n<td>Select when the formula calls for glucosamine HCl<\/td>\n<td>Select when the formula calls for glucosamine sulfate<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/section><section class=\"g-section\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Technical Reference<\/p>\n<h2>GlcNAc Technical Specification Reference<\/h2>\n<p>Technical points that may vary by selected grade or production route should be confirmed against the applicable product specification.<\/p>\n<\/div>\n<div class=\"g-table-wrap\">\n<table>\n<thead>\n<tr>\n<th>Parameter<\/th>\n<th>Reference \/ Review Point<\/th>\n<th>Basis<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>USP-NF Assay Reference<\/td>\n<td>98.0%\u2013102.0%, calculated on the dried basis<\/td>\n<td class=\"g-result\">Pharmacopeial reference<\/td>\n<\/tr>\n<tr>\n<td>Batch Assay<\/td>\n<td>Confirm on the applicable GlcNAc COA for the selected material.<\/td>\n<td class=\"g-result\">Batch specific<\/td>\n<\/tr>\n<tr>\n<td>Particle Size<\/td>\n<td>Confirm the particle-size specification required for the finished dosage form.<\/td>\n<td class=\"g-result\">Product specific<\/td>\n<\/tr>\n<tr>\n<td>Source &amp; Allergen<\/td>\n<td>Confirm the production source and supporting allergen declaration for the selected material.<\/td>\n<td class=\"g-result\">Source specific<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/section><section class=\"g-section g-section-soft\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Source &amp; Allergen Review<\/p>\n<h2>Source &amp; Allergen Considerations<\/h2>\n<p>The production route affects source and allergen documentation, so the specific material should be matched to the intended product positioning.<\/p>\n<\/div>\n<div class=\"g-source-grid\">\n<article class=\"g-source-card\">\n<h3>Shellfish-Linked Source<\/h3>\n<p>When the production route is linked to crustacean-derived materials, review the source,\n            species information, allergen statement and cross-contact information before making\n            shellfish-related label decisions.<\/p>\n<\/article>\n<article class=\"g-source-card\">\n<h3>Fermentation \/ Non-Shellfish Source<\/h3>\n<p>Some GlcNAc suppliers use fermentation or other non-shellfish routes. The production\n            route, substrate and supporting declarations should be verified for the specific material\n            before using vegan, shellfish-free or similar positioning.<\/p>\n<\/article>\n<\/div>\n<\/div>\n<\/section><section class=\"g-section\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Formulation<\/p>\n<h2>N-Acetyl Glucosamine Formulation Formats<\/h2>\n<p>GlcNAc powder can be considered across several supplement formats, with processing needs determined by the complete formulation.<\/p>\n<\/div>\n<div class=\"g-app-grid\">\n<article class=\"g-app\">\n<span class=\"g-app-num\">01<\/span>\n<h3>Capsules<\/h3>\n<p>For capsule products, serving size, particle characteristics, powder flow and blend uniformity influence the finished manufacturing process.<\/p>\n<\/article>\n<article class=\"g-app\">\n<span class=\"g-app-num\">02<\/span>\n<h3>Tablets<\/h3>\n<p>Tablet development may need to account for compression behavior, excipient compatibility and the physical characteristics of the complete blend.<\/p>\n<\/article>\n<article class=\"g-app\">\n<span class=\"g-app-num\">03<\/span>\n<h3>Gummies &amp; Chewables<\/h3>\n<p>For gummies and chewables, formulation development should account for heat exposure, moisture, pH, taste and active stability.<\/p>\n<\/article>\n<article class=\"g-app\">\n<span class=\"g-app-num\">04<\/span>\n<h3>Powder &amp; Drink Formats<\/h3>\n<p>For powder blends and drink formats, dispersion, flavor compatibility, moisture protection and blend uniformity are relevant to finished-product performance.<\/p>\n<\/article>\n<\/div>\n<\/div>\n<\/section><section class=\"g-section\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Human Research<\/p>\n<h2>Human Research on N-Acetyl Glucosamine<\/h2>\n<p>Human studies have evaluated oral N-acetyl glucosamine in relation to cartilage-metabolism biomarkers and joint-related outcomes. Study design, dose and whether GlcNAc was used alone or in combination are important when interpreting the findings for finished supplements.<\/p>\n<\/div>\n<div class=\"g-study-grid\">\n<article class=\"g-study\">\n<span class=\"g-study-id\">PubMed 27588069<\/span>\n<h3>Cartilage-Metabolism Biomarkers<\/h3>\n<p>\n            A randomized, double-blind, placebo-controlled study evaluated 500 mg\/day and\n            1,000 mg\/day of GlcNAc for 16 weeks in healthy adults without arthritis symptoms.\n            The study assessed C2C, PIICP and the C2C\/PIICP ratio.\n          <\/p>\n<div class=\"g-study-meta\">\n<span>Population<\/span>\n<strong>Healthy adults<\/strong>\n<span>Dose<\/span>\n<strong>500 or 1,000 mg\/day<\/strong>\n<span>Duration<\/span>\n<strong>16 weeks<\/strong>\n<\/div>\n<\/article>\n<article class=\"g-study\">\n<span class=\"g-study-id\">PubMed 26178634<\/span>\n<h3>GlcNAc + Chondroitin<\/h3>\n<p>\n            A randomized, double-blind, placebo-controlled trial examined a combination of\n            N-acetyl glucosamine and chondroitin sulfate in Japanese adults with knee pain or stiffness.\n            The reported outcomes included self-reported knee function and pain-related measures.\n          <\/p>\n<div class=\"g-study-meta\">\n<span>Intervention<\/span>\n<strong>GlcNAc + chondroitin sulfate<\/strong>\n<span>Duration<\/span>\n<strong>24 weeks<\/strong>\n<span>Population<\/span>\n<strong>Adults with knee symptoms<\/strong>\n<\/div>\n<\/article>\n<article class=\"g-study\">\n<span class=\"g-study-id\">PubMed 28757514<\/span>\n<h3>GlcNAc + Proteoglycan<\/h3>\n<p>\n            A 12-week open study evaluated a tablet containing GlcNAc and proteoglycan in subjects\n            with knee pain, using VAS, JKOM and JOA outcomes.\n          <\/p>\n<div class=\"g-study-meta\">\n<span>Intervention<\/span>\n<strong>GlcNAc + proteoglycan<\/strong>\n<span>Duration<\/span>\n<strong>12 weeks<\/strong>\n<span>Design<\/span>\n<strong>Open study<\/strong>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"g-note\">\n        These studies should not be interpreted as proof that GlcNAc alone treats osteoarthritis.\n        In particular, combination studies cannot isolate the contribution of GlcNAc from the other ingredients.\n      <\/div>\n<\/div>\n<\/section><section class=\"g-section g-section-soft\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Project Support<\/p>\n<h2>Technical &amp; Commercial Support<\/h2>\n<p>Additional product and project information can be coordinated as your formulation moves toward commercial sourcing.<\/p>\n<\/div>\n<div class=\"g-selection\"><div class=\"g-support-grid\"><article class=\"g-support-card\"><h3>Product Information<\/h3><p>Request available technical information for the GlcNAc material being discussed.<\/p><\/article><article class=\"g-support-card\"><h3>Formulation Discussion<\/h3><p>Discuss the intended dosage form and any material characteristics relevant to the formulation.<\/p><\/article><article class=\"g-support-card\"><h3>Commercial Coordination<\/h3><p>Continue quantity, quotation and purchasing discussions directly with the Gensei team.<\/p><\/article><\/div><\/div>\n<\/div>\n<\/section><section class=\"g-section g-section-soft\">\n<div class=\"g-wrap\">\n<div class=\"g-section-head\">\n<p class=\"g-kicker\">Regulatory Reference<\/p>\n<h2>Market &amp; Regulatory Considerations<\/h2>\n<p>Requirements for GlcNAc can vary with intended use, production source and destination market.<\/p>\n<\/div>\n<div class=\"g-compare-grid\">\n<article class=\"g-info-card\">\n<h3>United States<\/h3>\n<p>\n            USP-NF includes a N-Acetylglucosamine monograph that can serve as a pharmacopeial quality\n            reference. A monograph is not, by itself, authorization of a finished supplement.\n          <\/p>\n<\/article>\n<article class=\"g-info-card\">\n<h3>European Union<\/h3>\n<p>\n            The European Commission's 2026 public Novel Food application list includes an application\n            for N-acetylglucosamine from Shandong Runhan Biotechnology Co., Ltd. This should not be\n            interpreted as a blanket authorization for every GlcNAc material or use.\n          <\/p>\n<\/article>\n<\/div>\n<div class=\"g-note\">\n        Confirm the current requirements for the exact material, source and intended finished-product use\n        before finalizing labels or market-entry plans.\n      <\/div>\n<\/div>\n<\/section><section class=\"g-inquiry-section\" id=\"glcnac-inquiry\">\n<div class=\"g-wrap g-inquiry-grid\">\n<div class=\"g-inquiry-copy\">\n<div class=\"g-inquiry-pill\">N-Acetyl Glucosamine Inquiry<\/div>\n<h2>Discuss Your GlcNAc Ingredient Project<\/h2><p class=\"\">Send your project details and our team will follow up directly to continue the ingredient and commercial discussion.<\/p>\n<div class=\"g-inquiry-flow\"><div class=\"g-inquiry-step\"><span>01<\/span><div><h3>Inquiry Review<\/h3><p>Your message is routed for product and commercial follow-up.<\/p><\/div><\/div><div class=\"g-inquiry-step\"><span>02<\/span><div><h3>Direct Follow-Up<\/h3><p>A member of our team responds to continue the discussion with you.<\/p><\/div><\/div><div class=\"g-inquiry-step\"><span>03<\/span><div><h3>Next-Step Coordination<\/h3><p>Further requests can be coordinated directly as the project moves forward.<\/p><\/div><\/div><\/div><\/div>\n<div class=\"g-form-card\">\n<h3>Send Your Inquiry<\/h3><p class=\"g-form-intro\">Send us your company details and GlcNAc requirement.<\/p>\n        \n<div class=\"wpcf7 no-js\" id=\"wpcf7-f74-o1\" lang=\"zh-CN\" dir=\"ltr\" data-wpcf7-id=\"74\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/de\/wp-json\/wp\/v2\/pages\/4817#wpcf7-f74-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"\u7559\u8a00\u8868\u5355\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"74\" \/><input type=\"hidden\" 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Gensei supplies [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":4815,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-4817","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"trp-custom-language-flag":false},"uagb_author_info":{"display_name":"collagensei.com","author_link":"https:\/\/collagensei.com\/de\/author\/collagensei\/"},"uagb_comment_info":0,"uagb_excerpt":"Joint Health Ingredient N-Acetyl Glucosamine Powder Supplier N-Acetyl-D-Glucosamine (GlcNAc \/ NAG) powder for joint-health and specialty supplement formulations. 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