{"id":4858,"date":"2025-03-20T14:44:49","date_gmt":"2025-03-20T06:44:49","guid":{"rendered":"https:\/\/collagensei.com\/?page_id=4858"},"modified":"2026-10-20T13:08:22","modified_gmt":"2026-10-20T05:08:22","slug":"5%e3%83%9e%e3%82%bd%e7%b2%89","status":"publish","type":"page","link":"https:\/\/collagensei.com\/ja\/vitamins-supplier\/5-mthf-powder\/","title":{"rendered":"5-MTHF\u30d1\u30a6\u30c0\u30fc"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"4858\" class=\"elementor elementor-4858\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-38be80d e-con-full e-flex e-con e-parent\" data-id=\"38be80d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-604783d elementor-widget elementor-widget-html\" data-id=\"604783d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<style>\n\n.gensei-mthf-page{\n  position:relative;\n  left:50%;\n  transform:translateX(-50%);\n  width:100vw;\n  max-width:100vw;\n  overflow-x:clip;\n  --g-blue:#356486;\n  --g-blue-dark:#274d68;\n  --g-blue-soft:#edf3f7;\n  --g-ink:#1f2b33;\n  --g-muted:#66737c;\n  --g-line:#dbe3e8;\n  --g-bg:#f7f9fa;\n  --g-shadow:0 14px 36px rgba(38,70,91,.08);\n  font-family:inherit;\n  color:var(--g-ink);\n  line-height:1.6;\n}\n\n.gensei-mthf-page *,\n.gensei-mthf-page *::before,\n.gensei-mthf-page *::after{\n  box-sizing:border-box;\n}\n\n.gensei-mthf-page a{\n  text-decoration:none;\n}\n\n.gensei-mthf-page .g-wrap{\n  width:min(1320px,calc(100% - 48px));\n  margin:0 auto;\n}\n\n.gensei-mthf-page .g-hero{\n  padding:78px 0 62px;\n  background:\n    radial-gradient(circle at 84% 10%,rgba(53,100,134,.11),transparent 27%),\n    linear-gradient(180deg,#ffffff 0%,#f7f9fa 100%);\n  border-bottom:1px solid var(--g-line);\n}\n\n.gensei-mthf-page .g-hero-grid{\n  display:grid;\n  grid-template-columns:minmax(0,1.05fr) minmax(430px,.95fr);\n  gap:58px;\n  align-items:center;\n}\n\n.gensei-mthf-page .g-eyebrow{\n  margin:0 0 13px;\n  color:var(--g-blue);\n  font-size:12px;\n  font-weight:800;\n  letter-spacing:.14em;\n  text-transform:uppercase;\n}\n\n.gensei-mthf-page .g-hero h1{\n  max-width:850px;\n  margin:0 0 20px;\n  font-size:clamp(40px,4.7vw,60px);\n  line-height:1.03;\n  letter-spacing:-.038em;\n  color:var(--g-ink);\n}\n\n.gensei-mthf-page .g-lead{\n  max-width:760px;\n  margin:0 0 28px;\n  color:var(--g-muted);\n  font-size:18px;\n  line-height:1.78;\n}\n\n.gensei-mthf-page .g-actions{\n  display:flex;\n  flex-wrap:wrap;\n}\n\n.gensei-mthf-page .g-btn{\n  display:inline-flex;\n  align-items:center;\n  justify-content:center;\n  min-height:49px;\n  padding:0 21px;\n  border-radius:10px;\n  border:1px solid transparent;\n  font-weight:800;\n  transition:.2s ease;\n}\n\n.gensei-mthf-page .g-btn-primary{\n  background:var(--g-blue);\n  color:#fff;\n}\n\n.gensei-mthf-page .g-btn-primary:hover{\n  background:var(--g-blue-dark);\n  color:#fff;\n  transform:translateY(-1px);\n}\n\n.gensei-mthf-page .g-hero-image{\n  width:100%;\n  max-width:560px;\n  aspect-ratio:1 \/ 1;\n  justify-self:end;\n  overflow:hidden;\n  border:1px solid var(--g-line);\n  border-radius:24px;\n  background:#eef3f6;\n  box-shadow:var(--g-shadow);\n  position:relative;\n}\n\n.gensei-mthf-page .g-image-placeholder{\n  position:absolute;\n  inset:0;\n  display:flex;\n  align-items:center;\n  justify-content:center;\n  padding:30px;\n  text-align:center;\n  color:var(--g-blue-dark);\n  font-size:20px;\n  font-weight:800;\n}\n\n.gensei-mthf-page .g-hero-image img{\n  position:absolute;\n  inset:0;\n  display:block;\n  width:100%;\n  height:100%;\n  min-width:100%;\n  min-height:100%;\n  max-width:none;\n  object-fit:cover;\n  object-position:center center;\n  margin:0;\n  padding:0;\n  border:0;\n}\n\n.gensei-mthf-page .g-section{\n  padding:74px 0;\n}\n\n.gensei-mthf-page .g-section-soft{\n  background:var(--g-bg);\n  border-top:1px solid var(--g-line);\n  border-bottom:1px solid var(--g-line);\n}\n\n.gensei-mthf-page .g-section-head{\n  max-width:920px;\n  margin:0 0 32px;\n}\n\n.gensei-mthf-page .g-section-head h2{\n  margin:0 0 11px;\n  font-size:clamp(30px,3vw,39px);\n  line-height:1.12;\n  letter-spacing:-.028em;\n}\n\n.gensei-mthf-page .g-section-head p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:16px;\n  line-height:1.72;\n}\n\n.gensei-mthf-page .g-kicker{\n  margin:0 0 10px;\n  color:var(--g-blue);\n  font-size:12px;\n  font-weight:800;\n  letter-spacing:.12em;\n  text-transform:uppercase;\n}\n\n.gensei-mthf-page .g-facts{\n  display:grid;\n  grid-template-columns:repeat(4,1fr);\n  gap:14px;\n}\n\n.gensei-mthf-page .g-fact{\n  min-height:138px;\n  padding:23px;\n  background:#fff;\n  border:1px solid var(--g-line);\n  border-radius:16px;\n  box-shadow:0 8px 24px rgba(38,70,91,.04);\n}\n\n.gensei-mthf-page .g-fact span{\n  display:block;\n  margin-bottom:8px;\n  color:var(--g-muted);\n  font-size:12px;\n  font-weight:700;\n  letter-spacing:.06em;\n  text-transform:uppercase;\n}\n\n.gensei-mthf-page .g-fact strong{\n  display:block;\n  color:var(--g-ink);\n  font-size:18px;\n  line-height:1.4;\n  overflow-wrap:anywhere;\n}\n\n.gensei-mthf-page .g-standard-grid{\n  display:grid;\n  grid-template-columns:1.1fr .9fr;\n  gap:22px;\n}\n\n.gensei-mthf-page .g-standard-card{\n  padding:32px;\n  background:#fff;\n  border:1px solid var(--g-line);\n  border-radius:20px;\n  box-shadow:0 8px 24px rgba(38,70,91,.04);\n}\n\n.gensei-mthf-page .g-standard-card h3{\n  margin:0 0 13px;\n  color:var(--g-blue-dark);\n  font-size:25px;\n  line-height:1.2;\n}\n\n.gensei-mthf-page .g-standard-card p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:15px;\n  line-height:1.78;\n}\n\n.gensei-mthf-page .g-standard-card strong{\n  color:var(--g-ink);\n}\n\n.gensei-mthf-page .g-table-wrap{\n  overflow:auto;\n  border:1px solid var(--g-line);\n  border-radius:18px;\n  background:#fff;\n  box-shadow:var(--g-shadow);\n}\n\n.gensei-mthf-page table{\n  width:100%;\n  min-width:900px;\n  border-collapse:collapse;\n}\n\n.gensei-mthf-page th,\n.gensei-mthf-page td{\n  padding:14px 15px;\n  border-bottom:1px solid var(--g-line);\n  text-align:left;\n  vertical-align:top;\n  font-size:14px;\n}\n\n.gensei-mthf-page thead th{\n  background:var(--g-blue);\n  color:#fff;\n  font-weight:800;\n  position:sticky;\n  top:0;\n  z-index:1;\n}\n\n.gensei-mthf-page .g-group td{\n  padding:10px 15px;\n  background:var(--g-blue-soft);\n  color:var(--g-blue-dark);\n  font-weight:800;\n  letter-spacing:.02em;\n}\n\n.gensei-mthf-page tbody tr:last-child td{\n  border-bottom:none;\n}\n\n.gensei-mthf-page .g-result{\n  color:var(--g-blue-dark);\n  font-weight:800;\n}\n\n.gensei-mthf-page .g-quality-grid{\n  display:grid;\n  grid-template-columns:repeat(3,1fr);\n  gap:14px;\n}\n\n.gensei-mthf-page .g-quality-card{\n  padding:27px;\n  background:#fff;\n  border:1px solid var(--g-line);\n  border-radius:18px;\n  box-shadow:0 8px 24px rgba(38,70,91,.04);\n}\n\n.gensei-mthf-page .g-quality-card h3{\n  margin:0 0 9px;\n  color:var(--g-blue-dark);\n  font-size:21px;\n  line-height:1.24;\n}\n\n.gensei-mthf-page .g-quality-card p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:14px;\n  line-height:1.72;\n}\n\n.gensei-mthf-page .g-application-grid{\n  display:grid;\n  grid-template-columns:repeat(3,1fr);\n  gap:14px;\n}\n\n.gensei-mthf-page .g-application{\n  padding:25px;\n  background:#fff;\n  border:1px solid var(--g-line);\n  border-radius:17px;\n  box-shadow:0 8px 24px rgba(38,70,91,.04);\n}\n\n.gensei-mthf-page .g-application h3{\n  margin:0 0 9px;\n  color:var(--g-ink);\n  font-size:20px;\n  line-height:1.25;\n}\n\n.gensei-mthf-page .g-application p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:14px;\n  line-height:1.72;\n}\n\n.gensei-mthf-page .g-fit{\n  display:grid;\n  grid-template-columns:1.08fr .92fr;\n  gap:28px;\n}\n\n.gensei-mthf-page .g-fit-main,\n.gensei-mthf-page .g-fit-side{\n  padding:32px;\n  border-radius:20px;\n}\n\n.gensei-mthf-page .g-fit-main{\n  background:#fff;\n  border:1px solid var(--g-line);\n  box-shadow:var(--g-shadow);\n}\n\n.gensei-mthf-page .g-fit-side{\n  background:var(--g-blue-soft);\n  border:1px solid #d6e2e9;\n}\n\n.gensei-mthf-page .g-fit h3{\n  margin:0 0 12px;\n  color:var(--g-blue-dark);\n  font-size:25px;\n  line-height:1.22;\n}\n\n.gensei-mthf-page .g-fit p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:15px;\n  line-height:1.75;\n}\n\n.gensei-mthf-page .g-fit-list{\n  display:grid;\n  grid-template-columns:repeat(2,1fr);\n  gap:12px;\n  margin-top:23px;\n}\n\n.gensei-mthf-page .g-fit-item{\n  padding:17px;\n  background:var(--g-bg);\n  border:1px solid var(--g-line);\n  border-radius:14px;\n}\n\n.gensei-mthf-page .g-fit-item strong{\n  display:block;\n  margin-bottom:5px;\n  color:var(--g-blue-dark);\n  font-size:15px;\n}\n\n.gensei-mthf-page .g-fit-item span{\n  display:block;\n  color:var(--g-muted);\n  font-size:13px;\n  line-height:1.58;\n}\n\n.gensei-mthf-page .g-doc-grid{\n  display:grid;\n  grid-template-columns:repeat(3,1fr);\n  gap:14px;\n}\n\n.gensei-mthf-page .g-doc{\n  padding:24px;\n  background:#fff;\n  border:1px solid var(--g-line);\n  border-radius:17px;\n  box-shadow:0 8px 24px rgba(38,70,91,.04);\n}\n\n.gensei-mthf-page .g-doc h3{\n  margin:0 0 9px;\n  color:var(--g-blue-dark);\n  font-size:20px;\n  line-height:1.2;\n}\n\n.gensei-mthf-page .g-doc p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:14px;\n  line-height:1.72;\n}\n\n.gensei-mthf-page .g-packaging{\n  display:grid;\n  grid-template-columns:1fr 1fr;\n  gap:18px;\n}\n\n.gensei-mthf-page .g-pack-card{\n  padding:30px;\n  background:#fff;\n  border:1px solid var(--g-line);\n  border-radius:20px;\n  box-shadow:0 8px 24px rgba(38,70,91,.04);\n}\n\n.gensei-mthf-page .g-pack-card h3{\n  margin:0 0 13px;\n  color:var(--g-blue-dark);\n  font-size:25px;\n  line-height:1.2;\n}\n\n.gensei-mthf-page .g-pack-card p{\n  margin:0;\n  color:var(--g-muted);\n  font-size:15px;\n  line-height:1.75;\n}\n\n.gensei-mthf-page .g-storage-list{\n  display:grid;\n  gap:12px;\n  margin:19px 0 0;\n  padding:0;\n  list-style:none;\n}\n\n.gensei-mthf-page .g-storage-list li{\n  position:relative;\n  padding:14px 16px 14px 39px;\n  background:#fff;\n  border:1px solid #d6e2e9;\n  border-radius:12px;\n  color:var(--g-blue-dark);\n  font-size:14px;\n  line-height:1.55;\n}\n\n.gensei-mthf-page .g-storage-list li::before{\n  content:\"\";\n  position:absolute;\n  left:16px;\n  top:21px;\n  width:7px;\n  height:7px;\n  border-radius:50%;\n  background:var(--g-blue);\n}\n\n.gensei-mthf-page .g-inquiry-section{\n  padding:78px 0;\n  background:\n    radial-gradient(circle at 12% 22%,rgba(53,100,134,.09),transparent 26%),\n    linear-gradient(180deg,#f5f8fa 0%,#eef3f6 100%);\n  border-top:1px solid var(--g-line);\n  scroll-margin-top:30px;\n}\n\n.gensei-mthf-page .g-inquiry-grid{\n  display:grid;\n  grid-template-columns:minmax(0,1fr) minmax(420px,.92fr);\n  gap:54px;\n  align-items:center;\n}\n\n.gensei-mthf-page .g-inquiry-copy{\n  max-width:660px;\n}\n\n.gensei-mthf-page .g-inquiry-pill{\n  display:inline-flex;\n  align-items:center;\n  gap:8px;\n  padding:8px 13px;\n  margin-bottom:22px;\n  border:1px solid #c9d8e2;\n  border-radius:999px;\n  background:rgba(255,255,255,.72);\n  color:var(--g-blue);\n  font-size:13px;\n  font-weight:800;\n}\n\n.gensei-mthf-page .g-inquiry-pill::before{\n  content:\"\";\n  width:7px;\n  height:7px;\n  border-radius:50%;\n  background:var(--g-blue);\n}\n\n.gensei-mthf-page .g-inquiry-copy h2{\n  max-width:650px;\n  margin:0 0 18px;\n  font-size:clamp(38px,4.6vw,56px);\n  line-height:1.04;\n  letter-spacing:-.035em;\n  color:var(--g-blue-dark);\n}\n\n.gensei-mthf-page .g-inquiry-copy > p{\n  max-width:620px;\n  margin:0;\n  color:#5c6a74;\n  font-size:17px;\n  line-height:1.75;\n}\n\n.gensei-mthf-page .g-inquiry-points{\n  display:flex;\n  flex-wrap:wrap;\n  gap:10px;\n  margin-top:27px;\n}\n\n.gensei-mthf-page .g-inquiry-point{\n  padding:9px 13px;\n  border:1px solid #cbd9e2;\n  border-radius:999px;\n  background:#fff;\n  color:var(--g-blue-dark);\n  font-size:13px;\n  font-weight:800;\n}\n\n\n.gensei-mthf-page .g-quote-guide{\n  margin-top:30px;\n  padding-top:27px;\n  border-top:1px solid #d5e0e7;\n}\n\n.gensei-mthf-page .g-quote-guide h3{\n  margin:0 0 7px;\n  color:var(--g-blue-dark);\n  font-size:20px;\n  line-height:1.25;\n}\n\n.gensei-mthf-page .g-quote-guide > p{\n  max-width:620px;\n  margin:0;\n  color:#66737c;\n  font-size:14px;\n  line-height:1.65;\n}\n\n.gensei-mthf-page .g-quote-grid{\n  display:grid;\n  grid-template-columns:repeat(2,minmax(0,1fr));\n  gap:11px;\n  margin-top:17px;\n}\n\n.gensei-mthf-page .g-quote-item{\n  padding:15px 16px;\n  border:1px solid #d3dfe6;\n  border-radius:14px;\n  background:rgba(255,255,255,.78);\n}\n\n.gensei-mthf-page .g-quote-item strong{\n  display:block;\n  margin-bottom:4px;\n  color:var(--g-blue-dark);\n  font-size:14px;\n  line-height:1.35;\n}\n\n.gensei-mthf-page .g-quote-item span{\n  display:block;\n  color:#66737c;\n  font-size:12.5px;\n  line-height:1.55;\n}\n\n.gensei-mthf-page .g-quote-note{\n  margin-top:11px !important;\n  padding:12px 14px;\n  border-radius:12px;\n  background:rgba(255,255,255,.64);\n  color:#526773 !important;\n  font-size:12.5px !important;\n  line-height:1.55 !important;\n}\n\n.gensei-mthf-page .g-form-card{\n  padding:30px 30px 26px;\n  background:#fff;\n  border:1px solid #cfdae1;\n  border-radius:24px;\n  box-shadow:0 18px 44px rgba(38,70,91,.09);\n}\n\n.gensei-mthf-page .g-form-card h3{\n  margin:0 0 8px;\n  color:var(--g-blue-dark);\n  font-size:29px;\n  line-height:1.15;\n  letter-spacing:-.02em;\n}\n\n.gensei-mthf-page .g-form-card .wpcf7{\n  margin:0;\n}\n\n.gensei-mthf-page .g-form-card .wpcf7 p{\n  margin:0 0 16px;\n}\n\n.gensei-mthf-page .g-form-card .wpcf7 label{\n  display:block;\n  margin-bottom:7px;\n  color:var(--g-blue-dark);\n  font-size:14px;\n  font-weight:800;\n}\n\n.gensei-mthf-page .g-form-card input[type=\"text\"],\n.gensei-mthf-page .g-form-card input[type=\"email\"],\n.gensei-mthf-page .g-form-card input[type=\"tel\"],\n.gensei-mthf-page .g-form-card input[type=\"number\"],\n.gensei-mthf-page .g-form-card select,\n.gensei-mthf-page .g-form-card textarea{\n  width:100%;\n  min-height:44px;\n  padding:11px 13px;\n  border:1px solid #cbd9e2;\n  border-radius:12px;\n  background:#fbfcfd;\n  color:var(--g-ink);\n  outline:none;\n  box-shadow:0 3px 10px rgba(38,70,91,.035);\n  transition:.2s ease;\n}\n\n.gensei-mthf-page .g-form-card textarea{\n  min-height:150px;\n  resize:vertical;\n}\n\n.gensei-mthf-page .g-form-card input:focus,\n.gensei-mthf-page .g-form-card select:focus,\n.gensei-mthf-page .g-form-card textarea:focus{\n  border-color:var(--g-blue);\n  box-shadow:0 0 0 3px rgba(53,100,134,.09);\n}\n\n.gensei-mthf-page .g-form-card input[type=\"submit\"]{\n  width:100%;\n  min-height:52px;\n  border:0;\n  border-radius:999px;\n  background:var(--g-blue);\n  color:#fff;\n  font-weight:800;\n  cursor:pointer;\n  transition:.2s ease;\n}\n\n.gensei-mthf-page .g-form-card input[type=\"submit\"]:hover{\n  background:var(--g-blue-dark);\n  transform:translateY(-1px);\n}\n\n.gensei-mthf-page .g-form-card .wpcf7-spinner{\n  display:none;\n}\n\n@media(max-width:1100px){\n  .gensei-mthf-page .g-hero-grid{\n    grid-template-columns:1fr;\n  }\n\n  .gensei-mthf-page .g-hero-image{\n    max-width:none;\n    justify-self:stretch;\n  }\n\n  .gensei-mthf-page .g-facts{\n    grid-template-columns:repeat(2,1fr);\n  }\n\n  .gensei-mthf-page .g-standard-grid,\n  .gensei-mthf-page .g-fit,\n  .gensei-mthf-page .g-packaging{\n    grid-template-columns:1fr;\n  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0;max-width:900px;color:var(--g-muted);font-size:14px;line-height:1.7;text-align:center;\n}\n\n.gensei-mthf-page .g-spec-stack{display:grid;gap:14px;margin-top:22px;}\n.gensei-mthf-page .g-spec-group{\n  background:#fff;border:1px solid var(--g-line);border-radius:18px;overflow:hidden;box-shadow:var(--g-shadow);\n}\n.gensei-mthf-page .g-spec-group summary{\n  padding:17px 20px;color:var(--g-blue-dark);font-weight:800;cursor:pointer;\n}\n.gensei-mthf-page .g-spec-group summary span{float:right;color:var(--g-muted);font-size:12px;}\n\n.gensei-mthf-page .g-facts-identity{grid-template-columns:repeat(4,1fr);}\n.gensei-mthf-page .g-facts-batch{grid-template-columns:repeat(5,1fr);}\n.gensei-mthf-page .g-facts-identity .g-fact,\n.gensei-mthf-page .g-facts-batch .g-fact{text-align:center;}\n\n.gensei-mthf-page .g-hero .g-facts{\n  display:flex;flex-wrap:wrap;gap:9px;margin-top:18px;\n}\n.gensei-mthf-page .g-hero .g-fact{\n  min-height:0;padding:7px 11px;border-radius:999px;background:#fff;font-size:12px;\n}\n\n@media(max-width:1100px){\n  .gensei-mthf-page .g-overview,\n  .gensei-mthf-page .g-batch-meta,\n  .gensei-mthf-page .g-coa,\n  .gensei-mthf-page .g-facts-identity,\n  .gensei-mthf-page .g-facts-batch{grid-template-columns:repeat(2,1fr);}\n  .gensei-mthf-page .g-app-grid,\n  .gensei-mthf-page .g-process{grid-template-columns:1fr 1fr;}\n  .gensei-mthf-page .g-copy-grid{grid-template-columns:1fr;}\n}\n@media(max-width:640px){\n  .gensei-mthf-page .g-overview,\n  .gensei-mthf-page .g-batch-meta,\n  .gensei-mthf-page .g-coa,\n  .gensei-mthf-page .g-facts-identity,\n  .gensei-mthf-page .g-facts-batch,\n  .gensei-mthf-page .g-app-grid,\n  .gensei-mthf-page .g-process{grid-template-columns:1fr;}\n}\n\n<\/style>\n<div class=\"gensei-mthf-page\">\n<section class=\"g-hero\">\n <div class=\"g-wrap g-hero-grid\">\n  <div>\n   <div class=\"g-eyebrow\">5-MTHF \u00b7 L-Methylfolate Calcium \u00b7 Bulk Powder<\/div>\n   <h1>5-MTHF Powder (L-Methylfolate Calcium)<\/h1>\n   <p class=\"g-lead\">5-MTHF powder supplied as Calcium L-5-Methyltetrahydrofolate (L-Methylfolate Calcium) for dietary supplement formulation and bulk ingredient sourcing. The current COA identifies CAS 151533-22-1 and a USP-NF 2024 reference, with lot-specific assay, L-5-MTHF content and calcium results available for technical review.<\/p>\n   <div class=\"g-actions\"><a class=\"g-btn g-btn-primary\" href=\"#mthf-inquiry\">Request a Quote<\/a><\/div>\n   <div class=\"g-facts\"><span class=\"g-fact\">CAS 151533-22-1<\/span><span class=\"g-fact\">Calcium Salt<\/span><span class=\"g-fact\">Crystalline Powder<\/span><\/div>\n  <\/div>\n  <div class=\"g-image-card\"><img decoding=\"async\" src=\"https:\/\/collagensei.com\/wp-content\/uploads\/2026\/09\/Calcium-L-5-Methyltetrahydrofolate.webp\" alt=\"Calcium L-5-Methyltetrahydrofolate powder\" loading=\"eager\" fetchpriority=\"high\"><\/div>\n <\/div>\n<\/section>\n<section class=\"g-section\">\n <div class=\"g-wrap\">\n  <div class=\"g-section-head\"><h2>5-MTHF Supplement &amp; Formulation Applications<\/h2><p>L-Methylfolate Calcium provides 5-MTHF for formulations that specify a methylated folate source. These application examples are intended for formulation planning rather than finished-product efficacy claims.<\/p><\/div>\n  <div class=\"g-app-grid\">\n   <div class=\"g-app-card\"><h3>Prenatal &amp; Maternal Nutrition<\/h3><p>For prenatal multivitamins and maternal nutrition formulas that specify L-5-MTHF as their folate source, alongside ingredients such as choline, vitamin B12 and iron.<\/p><\/div>\n   <div class=\"g-app-card\"><h3>Methylated B-Complex<\/h3><p>For B-vitamin blends combining methylfolate with methylcobalamin, vitamin B6 and riboflavin in capsules or tablets.<\/p><\/div>\n   <div class=\"g-app-card\"><h3>Standalone Folate &amp; Multivitamins<\/h3><p>For single-ingredient methylfolate supplements and multivitamin formulas that call for a defined calcium L-5-MTHF ingredient.<\/p><\/div>\n  <\/div>\n <\/div>\n<\/section>\n<section class=\"g-section g-section-soft\">\n <div class=\"g-wrap\">\n  <div class=\"g-section-head\"><h2>5-MTHF, L-Methylfolate Calcium &amp; Other Folate Forms<\/h2><p>The folate source affects ingredient specifications, formulation behavior and finished-product labeling.<\/p><\/div>\n  <div class=\"g-copy-grid\">\n   <div class=\"g-copy-panel\"><h3>5-MTHF Is Distinct from Folic Acid<\/h3><p>L-5-MTHF is the methylated form of folate. Calcium L-5-MTHF supplies this form as a calcium salt, rather than as synthetic folic acid.<\/p><p>It can be selected for products positioned around methylated B vitamins or folic-acid-free ingredient lists. Finished-product claims and permitted uses depend on the destination market.<\/p><\/div>\n   <div class=\"g-copy-panel\"><h3>Calcium Salt vs. Glucosamine Salt<\/h3><p>Calcium L-5-MTHF and (6S)-5-MTHF glucosamine salt are different ingredient forms. Both supply methylfolate, but their solubility and formulation characteristics differ.<\/p><p>Calcium L-5-MTHF is a practical option to evaluate for dry blends, capsules and tablets. For beverages, liquid drops or heat-processed formats, solubility and stability should be established in the actual product matrix.<\/p><\/div>\n  <\/div>\n <\/div>\n<\/section>\n<section class=\"g-section\">\n <div class=\"g-wrap\">\n  <div class=\"g-section-head\"><h2>Formulation &amp; Manufacturing<\/h2><p>Ingredient selection and manufacturing conditions influence the amount of methylfolate delivered in each finished serving.<\/p><\/div>\n  <div class=\"g-process\">\n   <div class=\"g-process-item\"><h3>Active Folate Input<\/h3><p>The calcium-salt assay and L-5-MTHF content are distinct values. Calculate ingredient input using the active L-5-MTHF content of the applicable lot and the finished-product target.<\/p><\/div>\n   <div class=\"g-process-item\"><h3>Low-Dose Blend Uniformity<\/h3><p>Folate is often added at microgram levels per serving. Controlled weighing, premixing and blend-uniformity testing help achieve consistent distribution in larger production batches.<\/p><\/div>\n   <div class=\"g-process-item\"><h3>Finished-Product Stability<\/h3><p>Packaging, moisture, processing conditions and the surrounding formula can affect folate retention. Establish the appropriate overage and shelf life through finished-product stability studies.<\/p><\/div>\n  <\/div>\n <\/div>\n<\/section>\n<section class=\"g-section g-section-soft\">\n <div class=\"g-wrap\">\n  <div class=\"g-section-head\"><h2>Specifications &amp; Batch Test Results<\/h2><p>Calcium L-5-MTHF powder is supplied with a defined specification for identity, assay, related compounds, elemental impurities and microbiological quality.<\/p><\/div>\n  <div class=\"g-batch-meta\">\n   <div><span>Reference Batch<\/span><strong>NA260603<\/strong><\/div>\n   <div><span>Manufactured<\/span><strong>June 25, 2026<\/strong><\/div>\n   <div><span>Expiry<\/span><strong>June 24, 2028<\/strong><\/div>\n   <div><span>Origin \/ Method Reference<\/span><strong>China \u00b7 USP-NF 2024<\/strong><\/div>\n  <\/div>\n  <p class=\"g-method-note\">The results below apply to the reference batch. Test methods follow USP-NF 2024 unless otherwise stated; L-5-MTHF content is calculated.<\/p>\n      <div class=\"g-spec-stack\">\n        <details class=\"g-spec-group\" open>\n          <summary>Active Ingredient &amp; Related Compounds <span>14 test items<\/span><\/summary>\n          <div class=\"g-table-wrap\">\n            <table>\n              <thead>\n                <tr>\n                  <th>Test Item<\/th>\n                  <th>Specification<\/th>\n                  <th>Batch Result<\/th>\n                <\/tr>\n              <\/thead>\n              <tbody>\n                <tr><td>Assay (Anhydrous and solvent free)<\/td><td>95.0% - 102.0%<\/td><td>98.91%<\/td><\/tr>\n                <tr><td>L-5-MTHF<\/td><td>72.0% - 87.0%<\/td><td>80.95%<\/td><\/tr>\n                <tr><td>Calcium (Anhydrous and solvent free)<\/td><td>7.0% - 8.5%<\/td><td>8.14%<\/td><\/tr>\n                <tr><td>Total Related Compounds<\/td><td>NMT 2.5%<\/td><td>0.84%<\/td><\/tr>\n                <tr><td>4-Aminobenzoylglutamic Acid<\/td><td>NMT 0.5%<\/td><td>ND<\/td><\/tr>\n                <tr><td>4a-Hydroxy-5-Methyltetrahydrofolic Acid<\/td><td>NMT 1.0%<\/td><td>0.38%<\/td><\/tr>\n                <tr><td>(6R and 6S)-Mefox<\/td><td>NMT 1.0%<\/td><td>ND<\/td><\/tr>\n                <tr><td>Tetrahydrofolic Acid<\/td><td>NMT 0.5%<\/td><td>ND<\/td><\/tr>\n                <tr><td>7,8-Dihydrofolic Acid<\/td><td>NMT 0.5%<\/td><td>ND<\/td><\/tr>\n                <tr><td>Folic Acid<\/td><td>NMT 0.5%<\/td><td>ND<\/td><\/tr>\n                <tr><td>5,10-Methylenetetrahydropteroic Acid<\/td><td>NMT 0.5%<\/td><td>ND<\/td><\/tr>\n                <tr><td>5-Methyltetrahydropteroic Acid<\/td><td>NMT 0.5%<\/td><td>0.16%<\/td><\/tr>\n                <tr><td>Dimethyltetrahydrofolic Acid<\/td><td>NMT 0.15%<\/td><td>ND<\/td><\/tr>\n                <tr><td>Enantiomeric Impurity (D-5-methyltetrahydrofolate)<\/td><td>NMT 1.0%<\/td><td>0.50%<\/td><\/tr>\n              <\/tbody>\n            <\/table>\n          <\/div>\n        <\/details>\n\n        <details class=\"g-spec-group\">\n          <summary>Physical Control <span>7 test items<\/span><\/summary>\n          <div class=\"g-table-wrap\">\n            <table>\n              <thead>\n                <tr>\n                  <th>Test Item<\/th>\n                  <th>Specification<\/th>\n                  <th>Batch Result<\/th>\n                <\/tr>\n              <\/thead>\n              <tbody>\n                <tr><td>Appearance<\/td><td>White to light yellowish crystalline powder<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Identification<\/td><td>Retention time of the principal peak should conform with standard<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Water Content<\/td><td>6.0% - 17.0%<\/td><td>10.82%<\/td><\/tr>\n                <tr><td>Particle Size<\/td><td>NLT 90% pass 80 mesh<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Bulk Density<\/td><td>NLT 0.2 g\/ml<\/td><td>0.21 g\/ml<\/td><\/tr>\n                <tr><td>Residual Solvent - Ethanol<\/td><td>NMT 5000 ppm<\/td><td>ND<\/td><\/tr>\n                <tr><td>Residual Solvent - 2-Propanol<\/td><td>NMT 5000 ppm<\/td><td>ND<\/td><\/tr>\n              <\/tbody>\n            <\/table>\n          <\/div>\n        <\/details>\n\n        <details class=\"g-spec-group\">\n          <summary>Chemical Control <span>7 test items<\/span><\/summary>\n          <div class=\"g-table-wrap\">\n            <table>\n              <thead>\n                <tr>\n                  <th>Test Item<\/th>\n                  <th>Specification<\/th>\n                  <th>Batch Result<\/th>\n                <\/tr>\n              <\/thead>\n              <tbody>\n                <tr><td>Platinum<\/td><td>NMT 10 ppm<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Boron<\/td><td>NMT 50 ppm<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Chloride<\/td><td>NMT 0.5%<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Lead (Pb)<\/td><td>NMT 1.0 ppm<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Arsenic (As)<\/td><td>NMT 1.5 ppm<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Cadmium (Cd)<\/td><td>NMT 0.5 ppm<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Mercury (Hg)<\/td><td>NMT 1.5 ppm<\/td><td>Conforms<\/td><\/tr>\n              <\/tbody>\n            <\/table>\n          <\/div>\n        <\/details>\n\n        <details class=\"g-spec-group\">\n          <summary>Microbiological Control <span>8 test items<\/span><\/summary>\n          <div class=\"g-table-wrap\">\n            <table>\n              <thead>\n                <tr>\n                  <th>Test Item<\/th>\n                  <th>Specification<\/th>\n                  <th>Batch Result<\/th>\n                <\/tr>\n              <\/thead>\n              <tbody>\n                <tr><td>Total Plate Count<\/td><td>NMT 1000 cfu\/g<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Yeast &amp; Mold<\/td><td>NMT 100 cfu\/g<\/td><td>Conforms<\/td><\/tr>\n                <tr><td>Salmonella<\/td><td>Negative<\/td><td>Negative<\/td><\/tr>\n                <tr><td>E. Coli<\/td><td>Negative<\/td><td>Negative<\/td><\/tr>\n                <tr><td>Staphylococcus Aureus<\/td><td>Negative<\/td><td>Negative<\/td><\/tr>\n                <tr><td>Pseudomonas aeruginosa<\/td><td>Negative<\/td><td>Negative<\/td><\/tr>\n                <tr><td>Candida albicans<\/td><td>Negative<\/td><td>Negative<\/td><\/tr>\n                <tr><td>Clostridia<\/td><td>Negative<\/td><td>Negative<\/td><\/tr>\n              <\/tbody>\n            <\/table>\n          <\/div>\n        <\/details>\n      <\/div>\n\n\n  <p class=\"g-table-note\">ND = Not Detected &nbsp;\u00b7&nbsp; NMT = Not More Than &nbsp;\u00b7&nbsp; NLT = Not Less Than<\/p>\n <\/div>\n<\/section>\n<section class=\"g-section\">\n <div class=\"g-wrap\">\n  <div class=\"g-section-head\"><h2>Packaging &amp; Storage<\/h2><\/div>\n  <div class=\"g-supply-grid\">\n   <div class=\"g-supply-card\"><span>Pack Size<\/span><strong>1 kg or 5 kg<\/strong><p>Vacuum-packed in two inner plastic bags and a paper carton.<\/p><\/div>\n   <div class=\"g-supply-card\"><span>Storage Conditions<\/span><strong>Cool, dry place<\/strong><p>Keep the container tightly closed.<\/p><\/div>\n   <div class=\"g-supply-card\"><span>Shelf Life<\/span><strong>2 years<\/strong><p>When sealed and stored properly.<\/p><\/div>\n  <\/div>\n <\/div>\n<\/section>\n<section class=\"g-inquiry-section\" id=\"mthf-inquiry\">\n  <div class=\"g-wrap g-inquiry-grid\">\n    <div class=\"g-inquiry-copy\">\n      <div class=\"g-inquiry-pill\">5-MTHF \/ L-Methylfolate Calcium Inquiry<\/div>\n      <h2>Request Bulk L-Methylfolate Calcium Pricing<\/h2>\n      <p>Send your required quantity, destination and finished-product format for current 5-MTHF powder information, documentation availability and bulk pricing. This helps us align L-methylfolate calcium supply with your formulation and purchasing requirements.<\/p>\n      <div class=\"g-inquiry-points\"><span class=\"g-inquiry-point\">Specification<\/span><span class=\"g-inquiry-point\">Documentation<\/span><span class=\"g-inquiry-point\">Formulation<\/span><span class=\"g-inquiry-point\">Quotation<\/span><\/div>\n      <div class=\"g-quote-guide\">\n        <h3>For a Faster Quote<\/h3>\n        <p>Include the purchasing details below so we can prepare a more relevant commercial response to your 5-MTHF inquiry.<\/p>\n        <div class=\"g-quote-grid\"><div class=\"g-quote-item\"><strong>Required Quantity<\/strong><span>Share your estimated order quantity, trial quantity or recurring purchasing volume.<\/span><\/div><div class=\"g-quote-item\"><strong>Destination Market<\/strong><span>Provide the destination country or region for delivery and market-specific document review.<\/span><\/div><div class=\"g-quote-item\"><strong>Finished-Product Format<\/strong><span>Tell us whether the project is a prenatal, methylated B-complex, multivitamin or another folate formulation.<\/span><\/div><div class=\"g-quote-item\"><strong>Project Requirements<\/strong><span>Mention any packaging preference, supplier-qualification step or additional documentation your team needs.<\/span><\/div><\/div>\n        <p class=\"g-quote-note\"><strong>Still evaluating the formulation?<\/strong> Send the information already available and note which purchasing or technical points remain open.<\/p>\n      <\/div>\n    <\/div>\n    <div class=\"g-form-card\">\n      <h3>Send Your Inquiry<\/h3>\n      <p class=\"g-form-intro\">Share your company details and purchasing requirements.<\/p>\n      \n<div class=\"wpcf7 no-js\" id=\"wpcf7-f74-o1\" lang=\"zh-CN\" dir=\"ltr\" data-wpcf7-id=\"74\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/ja\/wp-json\/wp\/v2\/pages\/4858#wpcf7-f74-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"\u7559\u8a00\u8868\u5355\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"74\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.7\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"zh_CN\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f74-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/>\n<\/fieldset>\n<div class=\"stay-touch\">\n\t<ul>\n\t\t<li>\n\t\t\t<p><label> Name: <span class=\"wpcf7-form-control-wrap\" data-name=\"your-name\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"text\" name=\"your-name\" 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