{"id":13082,"date":"2026-07-24T11:07:55","date_gmt":"2026-07-24T03:07:55","guid":{"rendered":"https:\/\/collagensei.com\/?p=13082"},"modified":"2026-07-24T11:07:59","modified_gmt":"2026-07-24T03:07:59","slug":"vo-nang-gelatin-duoc-lam-tu-chat-gi","status":"publish","type":"post","link":"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/","title":{"rendered":"What Is a Gelatin Capsule Made Of? Ingredients, Sources and Quality Guide"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 ez-toc-wrap-left counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">M\u1ee5c l\u1ee5c<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"B\u1eadt\/t\u1eaft M\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Quick_Answer\" >C\u00e2u tr\u1ea3 l\u1eddi nhanh<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#What_Is_Gelatin\" >Gelatin l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#What_Is_a_Hard_Gelatin_Capsule_Made_Of\" >What Is a Hard Gelatin Capsule Made Of?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#What_Is_a_Soft_Gelatin_Capsule_Made_Of\" >What Is a Soft Gelatin Capsule Made Of?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Hard_vs_Soft_Gelatin_Capsule_Ingredients\" >Hard vs Soft Gelatin Capsule Ingredients<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Where_Does_Capsule_Gelatin_Come_From\" >Where Does Capsule Gelatin Come From?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Bovine_Gelatin\" >Gelatin b\u00f2<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Porcine_Gelatin\" >Gelatin heo<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Fish_Gelatin\" >Gelatin c\u00e1<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#What_Optional_Ingredients_May_Be_in_the_Capsule_Shell\" >What Optional Ingredients May Be in the Capsule Shell?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Colorants_and_Opacifiers\" >Colorants and Opacifiers<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Printing_Inks\" >Printing Inks<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Preservatives_and_Processing_Aids\" >Preservatives and Processing Aids<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#How_Are_Hard_Gelatin_Capsules_Made\" >How Are Hard Gelatin Capsules Made?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#How_Are_Softgels_Made\" >How Are Softgels Made?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Gelatin_vs_HPMC_and_Other_Plant-Based_Shells\" >Gelatin vs HPMC and Other Plant-Based Shells<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Labeling_and_Dietary_Suitability\" >Labeling and Dietary Suitability<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Quality_Specifications_to_Check\" >C\u00e1c ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng c\u1ea7n ki\u1ec3m tra<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#How_Supplement_Brands_Should_Choose_a_Capsule_Shell\" >C\u00e1c th\u01b0\u01a1ng hi\u1ec7u th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng n\u00ean l\u1ef1a ch\u1ecdn v\u1ecf vi\u00ean nang nh\u01b0 th\u1ebf n\u00e0o<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#RFP_Questions_for_a_Gelatin_Capsule_Manufacturer\" >RFP Questions for a Gelatin Capsule Manufacturer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Where_GENSEI_Fits\" >V\u1ecb tr\u00ed c\u1ee7a GENSEI<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Frequently_Asked_Questions\" >C\u00e2u h\u1ecfi th\u01b0\u1eddng g\u1eb7p<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#What_are_gelatin_capsules_made_of\" >What are gelatin capsules made of?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Are_gelatin_capsules_made_from_pork\" >Are gelatin capsules made from pork?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Are_gelatin_capsules_vegetarian\" >Are gelatin capsules vegetarian?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#What_is_the_difference_between_a_hard_gelatin_capsule_and_a_softgel\" >What is the difference between a hard gelatin capsule and a softgel?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-27\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Do_gelatin_capsules_contain_glycerin\" >Do gelatin capsules contain glycerin?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-28\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Are_bovine_gelatin_capsules_halal\" >Are bovine gelatin capsules halal?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-29\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Do_capsule_shell_ingredients_need_to_appear_on_the_label\" >Do capsule shell ingredients need to appear on the label?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-30\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#Final_Takeaway\" >\u0110i\u1ec3m ch\u00ednh c\u1ea7n ghi nh\u1edb<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-31\" href=\"https:\/\/collagensei.com\/vi\/what-is-a-gelatin-capsule-made-of\/#References\" >T\u00e0i li\u1ec7u tham kh\u1ea3o<\/a><\/li><\/ul><\/nav><\/div>\n\n<h2><span class=\"ez-toc-section\" id=\"Quick_Answer\"><\/span>C\u00e2u tr\u1ea3 l\u1eddi nhanh<span class=\"ez-toc-section-end\"><\/span><\/h2>\nA hard gelatin capsule shell is usually made from gelatin and water, with optional colorants, opacifiers and printing inks. A softgel shell usually contains gelatin, water and a plasticizer such as glycerin or sorbitol, plus optional colors or other processing ingredients. The exact formula, animal source and specifications vary by supplier and product.<\/p>\n<p>The shell should be evaluated separately from the capsule fill. Consumers may care about animal source and dietary suitability, while supplement brands also need identity, microbiological, contaminant, dissolution, stability and labeling documentation before production.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1000\" height=\"545\" src=\"https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/gelatin-capsule-shell-ingredients-comparison.webp\" alt=\"Gelatin capsule shell ingredients for hard capsules and softgels\" class=\"wp-image-23846\" srcset=\"https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/gelatin-capsule-shell-ingredients-comparison.webp 1000w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/gelatin-capsule-shell-ingredients-comparison-300x164.webp 300w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/gelatin-capsule-shell-ingredients-comparison-768x419.webp 768w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/gelatin-capsule-shell-ingredients-comparison-18x10.webp 18w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"What_Is_Gelatin\"><\/span>Gelatin l\u00e0 g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Gelatin is a protein ingredient produced by partial <a class=\"wpil_keyword_link\" href=\"https:\/\/collagensei.com\/vi\/keratin-thuy-phan-so-voi-protein-bo-tinh-che\/\" target=\"_blank\"  rel=\"noopener\" title=\"Keratin th\u1ee7y ph\u00e2n so v\u1edbi protein b\u00f2 tinh khi\u1ebft\" data-wpil-keyword-link=\"linked\"  data-wpil-monitor-id=\"3833\">ph\u1ea3n \u1ee9ng th\u1ee7y ph\u00e2n<\/a> of collagen-rich animal tissues. Commercial gelatin may be derived from bovine, porcine or fish sources. Its source, tissue, pretreatment and manufacturing process affect characteristics such as gel strength, viscosity, color, odor and capsule performance.<\/p>\n<p>A capsule specification should not rely on the word &#8220;gelatin&#8221; alone. Procurement teams should verify the species, tissue source, country of origin, Type A or Type B designation when relevant, and the supplier&#8217;s quality documentation. For a deeper production overview, see <a href=\"https:\/\/collagensei.com\/vi\/gelatin-duoc-san-xuat-nhu-the-nao\/\" target=\"_blank\" rel=\"noopener\">how gelatin is made<\/a>.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"What_Is_a_Hard_Gelatin_Capsule_Made_Of\"><\/span>What Is a Hard Gelatin Capsule Made Of?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A hard gelatin capsule is a two-piece shell consisting of a cap and body. The shell formula is commonly based on gelatin and purified water. Depending on the product and market, it may also contain approved colorants, opacifying agents and printing inks.<\/p>\n<p>Hard capsule manufacturers control solution viscosity, dipping conditions, drying, shell dimensions, moisture, mechanical strength and dissolution. The final shell composition and residual moisture are supplier- and process-specific, so universal percentages should not be presented as fixed values for every capsule.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"What_Is_a_Soft_Gelatin_Capsule_Made_Of\"><\/span>What Is a Soft Gelatin Capsule Made Of?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A soft gelatin capsule, or softgel, is a one-piece hermetically sealed shell. Its shell system generally contains gelatin, purified water and a plasticizer. Glycerin and sorbitol are common plasticizer options because they help create a flexible shell. The formula may also use approved colors, opacifiers, flavors or other processing ingredients when technically justified and legally permitted.<\/p>\n<p>The correct plasticizer system depends on the fill composition, shell-to-fill compatibility, target hardness, storage conditions and package. Softgel development therefore requires pilot work and stability testing rather than a universal gelatin-to-plasticizer ratio.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Hard_vs_Soft_Gelatin_Capsule_Ingredients\"><\/span>Hard vs Soft Gelatin Capsule Ingredients<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<table>\n  <thead>\n    <tr><th>Y\u1ebfu t\u1ed1<\/th><th>Vi\u00ean nang gelatin c\u1ee9ng<\/th><th>Soft Gelatin Capsule<\/th><\/tr>\n  <\/thead>\n  <tbody>\n    <tr><td>Shell design<\/td><td>Two-piece cap and body<\/td><td>One-piece sealed shell<\/td><\/tr>\n    <tr><td>Core shell ingredients<\/td><td>Gelatin and water<\/td><td>Gelatin, water and plasticizer<\/td><\/tr>\n    <tr><td>Common optional ingredients<\/td><td>Colorants, opacifiers and printing inks<\/td><td>Colorants, opacifiers, flavors or other approved processing ingredients<\/td><\/tr>\n    <tr><td>H\u00ecnh th\u1ee9c \u0111i\u1ec1n th\u00f4ng th\u01b0\u1eddng<\/td><td>Powders, granules, pellets or selected non-aqueous fills<\/td><td>Oils, suspensions, pastes and selected solutions<\/td><\/tr>\n    <tr><td>Critical development checks<\/td><td>Shell dimensions, brittleness, moisture, fill compatibility and dissolution<\/td><td>Plasticizer balance, seam integrity, leakage, migration, oxidation and dissolution<\/td><\/tr>\n  <\/tbody>\n<\/table>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1000\" height=\"545\" src=\"https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/hard-vs-soft-gelatin-capsule-composition.webp\" alt=\"Hard versus soft gelatin capsule composition and fill matrix\" class=\"wp-image-23848\" srcset=\"https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/hard-vs-soft-gelatin-capsule-composition.webp 1000w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/hard-vs-soft-gelatin-capsule-composition-300x164.webp 300w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/hard-vs-soft-gelatin-capsule-composition-768x419.webp 768w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/hard-vs-soft-gelatin-capsule-composition-18x10.webp 18w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Where_Does_Capsule_Gelatin_Come_From\"><\/span>Where Does Capsule Gelatin Come From?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"Bovine_Gelatin\"><\/span>Gelatin b\u00f2<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Bovine gelatin is commonly made from cattle hides, skin or bones. Buyers should request species and tissue documentation, country of origin, traceability and applicable BSE\/TSE statements. &#8220;BSE-free&#8221; should not be used as a vague absolute claim; documentation should describe the source materials and controls that apply to the exact ingredient.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Porcine_Gelatin\"><\/span>Gelatin heo<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Porcine gelatin is derived from pig skin or other porcine tissues. It is widely used in food and pharmaceutical applications but is not acceptable for halal products and may not meet kosher requirements. Certification depends on the exact source, process, facility and certifying body.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Fish_Gelatin\"><\/span>Gelatin c\u00e1<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Fish gelatin may be selected for certain religious, cultural or market-positioning needs. Its gel properties can differ from mammalian gelatin, and fish species, allergen assessment, supply consistency and certification should be verified. Fish origin alone does not automatically establish halal or kosher status.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"What_Optional_Ingredients_May_Be_in_the_Capsule_Shell\"><\/span>What Optional Ingredients May Be in the Capsule Shell?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"Colorants_and_Opacifiers\"><\/span>Colorants and Opacifiers<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Capsules may be transparent, colored or opaque. Any color additive must be permitted for the intended use and target market. Titanium dioxide requirements differ by market: it remains permitted for specified food uses in the United States under current FDA conditions, while E171 is no longer authorized as a food additive in the European Union. Brands selling food supplements in multiple markets should qualify a market-appropriate color system.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Printing_Inks\"><\/span>Printing Inks<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Capsules may be printed with product codes, logos or other identifiers. Ink components, migration controls, legibility and regulatory suitability should be included in the capsule specification and supplier documentation.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Preservatives_and_Processing_Aids\"><\/span>Preservatives and Processing Aids<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Not every gelatin capsule requires a preservative. The need depends on water activity, manufacturing controls, shell formulation and storage. Brands should request the complete shell ingredient declaration and should not assume that all processing materials are identical across suppliers.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1000\" height=\"545\" src=\"https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/capsule-colorants-tio2-market-checklist.webp\" alt=\"Gelatin capsule colorants titanium dioxide and market compliance checklist\" class=\"wp-image-23850\" srcset=\"https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/capsule-colorants-tio2-market-checklist.webp 1000w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/capsule-colorants-tio2-market-checklist-300x164.webp 300w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/capsule-colorants-tio2-market-checklist-768x419.webp 768w, https:\/\/collagensei.com\/wp-content\/uploads\/2025\/12\/capsule-colorants-tio2-market-checklist-18x10.webp 18w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"How_Are_Hard_Gelatin_Capsules_Made\"><\/span>How Are Hard Gelatin Capsules Made?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ol>\n  <li>Gelatin is hydrated and dissolved under controlled conditions.<\/li>\n  <li>Approved colors or other shell ingredients are added when required.<\/li>\n  <li>Metal pins are dipped into the gelatin solution to form the cap and body films.<\/li>\n  <li>The shells are dried under controlled temperature and humidity.<\/li>\n  <li>The dried shells are stripped, trimmed and joined.<\/li>\n  <li>Capsules are inspected for dimensions, defects, moisture and performance before release.<\/li>\n<\/ol>\n<p>During <a href=\"https:\/\/collagensei.com\/vi\/nha-san-xuat-thuc-pham-bo-sung-dang-vien-nang\/\" target=\"_blank\" rel=\"noopener\">S\u1ea3n xu\u1ea5t th\u1ef1c ph\u1ea9m b\u1ed5 sung d\u1ea1ng vi\u00ean nang<\/a>, the shell must also be qualified against the proposed fill, packaging and shelf-life conditions.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"How_Are_Softgels_Made\"><\/span>How Are Softgels Made?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ol>\n  <li>A gelatin mass is prepared with water, plasticizer and approved optional ingredients.<\/li>\n  <li>The fill material is prepared separately and checked for compatibility with the shell.<\/li>\n  <li>Two gelatin ribbons are formed and brought together in a rotary-die encapsulation process.<\/li>\n  <li>The fill is metered between the ribbons as the capsule is formed and sealed.<\/li>\n  <li>Softgels are dried, sorted, inspected and tested.<\/li>\n  <li>The final product is packaged to control moisture, oxygen, light and temperature as required.<\/li>\n<\/ol>\n<p>Reactive aldehydes, unsuitable solvents, excessive water migration or poor storage conditions can affect gelatin cross-linking and dissolution. Finished-product testing is therefore necessary even when the empty shell meets its incoming specification.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Gelatin_vs_HPMC_and_Other_Plant-Based_Shells\"><\/span>Gelatin vs HPMC and Other Plant-Based Shells<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>HPMC, pullulan and other non-gelatin materials are separate capsule-shell systems. HPMC is not a type of gelatin. A plant-derived shell may suit vegetarian positioning, but material name alone does not prove vegan, halal, kosher, non-GMO or allergen status. The exact formula, processing aids, facility and certificates still need review.<\/p>\n<p>For a technical comparison of shell behavior and formulation tradeoffs, review <a href=\"https:\/\/collagensei.com\/vi\/vien-nang-gelatin-so-voi-vien-nang-hpmc-danh-cho-nguoi-an-chay\/\" target=\"_blank\" rel=\"noopener\">gelatin vs HPMC capsules<\/a>.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Labeling_and_Dietary_Suitability\"><\/span>Labeling and Dietary Suitability<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n  <li>Distinguish capsule shell ingredients from the ingredients contained inside the capsule.<\/li>\n  <li>List the shell ingredients required by the target market; a phrase such as &#8220;vegetarian capsule&#8221; is not a complete ingredient declaration.<\/li>\n  <li>Declare added water, glycerin, colors and other ingredients when applicable under the relevant labeling rules.<\/li>\n  <li>Do not describe bovine gelatin as automatically halal or kosher.<\/li>\n  <li>Do not use &#8220;allergen-free&#8221; unless the claim has been reviewed against the formula, facility, supply chain and applicable law.<\/li>\n  <li>Confirm that color additives and printing inks are permitted in every market where the product will be sold.<\/li>\n<\/ul>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Quality_Specifications_to_Check\"><\/span>C\u00e1c ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng c\u1ea7n ki\u1ec3m tra<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<table>\n  <thead>\n    <tr><th>Quality Attribute<\/th><th>Nh\u1eefng \u0111i\u1ec1u c\u1ea7n ki\u1ec3m tra<\/th><th>T\u1ea1i sao \u0111i\u1ec1u n\u00e0y l\u1ea1i quan tr\u1ecdng<\/th><\/tr>\n  <\/thead>\n  <tbody>\n    <tr><td>B\u1ea3n s\u1eafc v\u00e0 ngu\u1ed3n g\u1ed1c<\/td><td>Gelatin identity, animal species, tissue, country of origin and traceability<\/td><td>Supports correct labeling, dietary suitability and source-risk review<\/td><\/tr>\n    <tr><td>Functional properties<\/td><td>Gel strength, viscosity and supplier-defined capsule performance specifications<\/td><td>Affects shell formation, mechanical properties and process consistency<\/td><\/tr>\n    <tr><td>Dimensions and appearance<\/td><td>Capsule size, cap\/body fit, color, print and visual defect limits<\/td><td>Supports filling-line performance and finished-product presentation<\/td><\/tr>\n    <tr><td>Moisture and mechanical behavior<\/td><td>Supplier moisture range, brittleness, elasticity and storage conditions<\/td><td>Reduces cracking, deformation and leakage risk<\/td><\/tr>\n    <tr><td>Vi sinh h\u1ecdc<\/td><td>Total counts and specified organism limits<\/td><td>Supports ingredient and finished-product release<\/td><\/tr>\n    <tr><td>C\u00e1c ch\u1ea5t g\u00e2y \u00f4 nhi\u1ec5m<\/td><td>Heavy metals and other risk-based tests<\/td><td>Supports market and product safety requirements<\/td><\/tr>\n    <tr><td>Dissolution or disintegration<\/td><td>Compendial or product-appropriate method and acceptance criteria<\/td><td>Confirms the finished dosage form performs as intended<\/td><\/tr>\n    <tr><td>Compatibility and stability<\/td><td>Fill interaction, cross-linking risk, package compatibility and shelf-life data<\/td><td>Incoming shell compliance does not guarantee finished-product performance<\/td><\/tr>\n    <tr><td>T\u00e0i li\u1ec7u<\/td><td>Specification, lot COA, TDS, SDS, origin statement and relevant certificates<\/td><td>H\u1ed7 tr\u1ee3 vi\u1ec7c \u0111\u00e1nh gi\u00e1 n\u0103ng l\u1ef1c nh\u00e0 cung c\u1ea5p v\u00e0 chu\u1ea9n b\u1ecb cho ho\u1ea1t \u0111\u1ed9ng ki\u1ec3m to\u00e1n<\/td><\/tr>\n  <\/tbody>\n<\/table>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"How_Supplement_Brands_Should_Choose_a_Capsule_Shell\"><\/span>C\u00e1c th\u01b0\u01a1ng hi\u1ec7u th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng n\u00ean l\u1ef1a ch\u1ecdn v\u1ecf vi\u00ean nang nh\u01b0 th\u1ebf n\u00e0o<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The best shell is the one that meets the product&#8217;s fill, market, dietary, processing and stability requirements. A transparent hard gelatin capsule may be suitable for a dry powder, while an opaque or printed shell may be chosen for light protection or brand identification. A softgel requires a compatible plasticizer system and fill that will not destabilize the shell.<\/p>\n<p>Brands should define the target markets, fill type, serving size, certification requirements, color system, package and shelf life before requesting quotations. The shell supplier and contract manufacturer should then document how the selected material is qualified for the finished product.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"RFP_Questions_for_a_Gelatin_Capsule_Manufacturer\"><\/span>RFP Questions for a Gelatin Capsule Manufacturer<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ol>\n  <li>Is the shell hard gelatin or soft gelatin, and what is the complete shell formula?<\/li>\n  <li>What animal species, tissue and country of origin apply to the gelatin?<\/li>\n  <li>Which Type A or Type B designation and functional specifications apply?<\/li>\n  <li>Which colors, opacifiers, printing inks, plasticizers or preservatives are used?<\/li>\n  <li>Are all shell ingredients permitted in the target markets?<\/li>\n  <li>What halal, kosher or other certificates apply to the exact shell and manufacturing site?<\/li>\n  <li>What BSE\/TSE and source-traceability documentation is available for bovine gelatin?<\/li>\n  <li>Which incoming and finished-product tests are included?<\/li>\n  <li>How is shell-to-fill compatibility evaluated?<\/li>\n  <li>How are cross-linking, dissolution, brittleness, leakage and moisture migration controlled?<\/li>\n  <li>What are the MOQ, sample quantity, tooling cost and lead time?<\/li>\n  <li>Can you provide recent lot COAs, specifications, batch records and stability options?<\/li>\n<\/ol>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Where_GENSEI_Fits\"><\/span>V\u1ecb tr\u00ed c\u1ee7a GENSEI<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>GENSEI supports hard-capsule and softgel projects, including shell selection, formulation review, pilot development, filling, packaging and quality planning. Brands can <a href=\"https:\/\/collagensei.com\/vi\/lien-he-voi-chung-toi\/\" target=\"_blank\" rel=\"noopener\">li\u00ean h\u1ec7 v\u1edbi GENSEI<\/a> with the target shell material, fill type, capsule size, market, certification needs and order quantity.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions\"><\/span>C\u00e2u h\u1ecfi th\u01b0\u1eddng g\u1eb7p<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"What_are_gelatin_capsules_made_of\"><\/span>What are gelatin capsules made of?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Hard gelatin capsule shells are generally made from gelatin and water, with optional colors, opacifiers and printing inks. Softgel shells usually also contain a plasticizer such as glycerin or sorbitol.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Are_gelatin_capsules_made_from_pork\"><\/span>Are gelatin capsules made from pork?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Some are. Gelatin capsules may use porcine, bovine or fish gelatin. The species should be verified from the product label or supplier documentation rather than assumed from the word &#8220;gelatin.&#8221;<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Are_gelatin_capsules_vegetarian\"><\/span>Are gelatin capsules vegetarian?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>No. Gelatin is animal-derived. Vegetarian shell alternatives may use HPMC, pullulan or other non-gelatin materials, subject to formula and certification review.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"What_is_the_difference_between_a_hard_gelatin_capsule_and_a_softgel\"><\/span>What is the difference between a hard gelatin capsule and a softgel?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>A hard capsule is a two-piece shell commonly filled with powders or granules. A softgel is a one-piece sealed shell that includes a plasticizer and is commonly used for oils, suspensions or pastes.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Do_gelatin_capsules_contain_glycerin\"><\/span>Do gelatin capsules contain glycerin?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Softgel shells commonly use glycerin, sorbitol or another plasticizer. Hard gelatin capsule shells are not normally defined by a plasticizer, although the exact supplier formula should be reviewed.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Are_bovine_gelatin_capsules_halal\"><\/span>Are bovine gelatin capsules halal?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Not automatically. Halal status depends on the cattle source, slaughter, processing, facility and valid certification for the exact capsule shell.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Do_capsule_shell_ingredients_need_to_appear_on_the_label\"><\/span>Do capsule shell ingredients need to appear on the label?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Applicable shell ingredients should be included in the ingredient declaration according to the target market&#8217;s labeling rules. A general phrase such as &#8220;vegetarian capsule&#8221; does not replace a complete ingredient declaration.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"Final_Takeaway\"><\/span>\u0110i\u1ec3m ch\u00ednh c\u1ea7n ghi nh\u1edb<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A gelatin capsule shell is not just &#8220;gelatin.&#8221; Hard shells generally contain gelatin and water, while softgels also use a plasticizer. Animal source, optional colors, printing inks, certifications, contaminant controls, dissolution, fill compatibility and labeling all matter. Consumers should check source and dietary suitability; brands should qualify the exact shell with lot documentation and finished-product testing.<\/p>\n\n\n\n<h2><span class=\"ez-toc-section\" id=\"References\"><\/span>T\u00e0i li\u1ec7u tham kh\u1ea3o<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ol>\n  <li><a href=\"https:\/\/www.fda.gov\/food\/information-consumers-using-dietary-supplements\/questions-and-answers-dietary-supplements\" target=\"_blank\" rel=\"noopener nofollow\">FDA: C\u00e2u h\u1ecfi v\u00e0 c\u00e2u tr\u1ea3 l\u1eddi v\u1ec1 th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng<\/a><\/li>\n  <li><a href=\"https:\/\/www.fda.gov\/food\/dietary-supplements-guidance-documents-regulatory-information\/dietary-supplement-labeling-guide-chapter-v-ingredient-labeling\" target=\"_blank\" rel=\"noopener nofollow\">FDA: Dietary Supplement Labeling Guide, Chapter V &#8211; Ingredient Labeling<\/a><\/li>\n  <li><a href=\"https:\/\/www.fda.gov\/inspections-compliance-enforcement-and-criminal-investigations\/warning-letters\/snac-system-inc-633434-02132023\" target=\"_blank\" rel=\"noopener nofollow\">FDA Warning Letter: Capsule Shell Ingredient Labeling<\/a><\/li>\n  <li><a href=\"https:\/\/www.fda.gov\/food\/hfp-constituent-updates\/fda-announces-final-rule-bovine-spongiform-encephalopathy\" target=\"_blank\" rel=\"noopener nofollow\">FDA: Final Rule on Bovine Spongiform Encephalopathy<\/a><\/li>\n  <li><a href=\"https:\/\/www.ecfr.gov\/current\/title-21\/chapter-I\/subchapter-B\/part-111\/subpart-E\" target=\"_blank\" rel=\"noopener nofollow\">21 CFR Part 111, Subpart E: Requirements for Components and Specifications<\/a><\/li>\n  <li><a href=\"https:\/\/www.fda.gov\/industry\/color-additives\/titanium-dioxide-color-additive-foods\" target=\"_blank\" rel=\"noopener nofollow\">FDA: Titanium Dioxide as a Color Additive in Foods<\/a><\/li>\n  <li><a href=\"https:\/\/eur-lex.europa.eu\/eli\/reg\/2022\/63\/oj\" target=\"_blank\" rel=\"noopener nofollow\">Commission Regulation (EU) 2022\/63 on Titanium Dioxide (E171)<\/a><\/li>\n  <li><a href=\"https:\/\/www.gelatin-gmia.com\/uploads\/1\/1\/8\/4\/118450438\/gmia_gelatin_manual_2019.pdf\" target=\"_blank\" rel=\"noopener nofollow\">Gelatin Manufacturers Institute of America: Gelatin Handbook<\/a><\/li>\n  <li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11468233\/\" target=\"_blank\" rel=\"noopener nofollow\">Softgel Shell Formulation and Manufacturing Review<\/a><\/li>\n  <li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0268005X1400232X\" target=\"_blank\" rel=\"noopener nofollow\">Gelatin Structure, Cross-Linking and Hard Capsule Dissolution<\/a><\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"<p>Quick Answer A hard gelatin capsule shell is usually made from gelatin and water, with optional colorants, opacifiers and printing [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":13087,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[535,99],"tags":[418,400,486,424,395,101,470],"class_list":["post-13082","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-capsule","category-gelatin","tag-capsule","tag-capsule-manufacturing","tag-capsule-supplement-manufacturer","tag-capsule-supplement-manufacturing","tag-custom-formula-supplements","tag-gelatin","tag-oem-manufacturing-service"],"_links":{"self":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts\/13082","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/comments?post=13082"}],"version-history":[{"count":2,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts\/13082\/revisions"}],"predecessor-version":[{"id":23853,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts\/13082\/revisions\/23853"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/media\/13087"}],"wp:attachment":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/media?parent=13082"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/categories?post=13082"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/tags?post=13082"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}