{"id":2074,"date":"2024-07-23T10:52:02","date_gmt":"2024-07-23T02:52:02","guid":{"rendered":"https:\/\/collagensei.com\/?p=2074"},"modified":"2024-07-24T09:35:46","modified_gmt":"2024-07-24T01:35:46","slug":"chiet-xuat-cay-ke-sua-kham-pha-cac-dac-tinh-va-ung-dung","status":"publish","type":"post","link":"https:\/\/collagensei.com\/vi\/milk-thistle-extract-unveiling-its-properties-and-applications\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa: Kh\u00e1m ph\u00e1 c\u00e1c \u0111\u1eb7c t\u00ednh v\u00e0 \u1ee9ng d\u1ee5ng"},"content":{"rendered":"

Gi\u1edbi thi\u1ec7u<\/strong><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa, \u0111\u01b0\u1ee3c chi\u1ebft xu\u1ea5t t\u1eeb h\u1ea1t c\u1ee7a c\u00e2y k\u1ebf s\u1eefa (*Silybum marianum*), \u0111\u00e3 \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn nh\u1edd c\u00e1c \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c li\u1ec7u m\u1ea1nh m\u1ebd v\u00e0 l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb c\u1ee7a n\u00f3. B\u00e0i vi\u1ebft to\u00e0n di\u1ec7n n\u00e0y t\u00ecm hi\u1ec3u v\u1ec1 b\u1ea3n ch\u1ea5t c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa, bao g\u1ed3m c\u00e1c \u0111\u1eb7c t\u00ednh v\u1eadt l\u00fd v\u00e0 h\u00f3a h\u1ecdc, ngu\u1ed3n g\u1ed1c, c\u00e1c \u1ee9ng d\u1ee5ng \u0111a d\u1ea1ng trong nhi\u1ec1u l\u0129nh v\u1ef1c kh\u00e1c nhau, nh\u1eefng l\u1ee3i \u00edch ti\u1ec1m n\u0103ng \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe, c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 li\u00ean quan, c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 quy \u0111\u1ecbnh ph\u00e1p l\u00fd, c\u0169ng nh\u01b0 c\u00e1c h\u01b0\u1edbng nghi\u00ean c\u1ee9u trong t\u01b0\u01a1ng lai.<\/span><\/p>\n

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Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 g\u00ec?<\/strong><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 m\u1ed9t lo\u1ea1i d\u01b0\u1ee3c li\u1ec7u \u0111\u01b0\u1ee3c chi\u1ebft xu\u1ea5t t\u1eeb h\u1ea1t c\u1ee7a c\u00e2y k\u1ebf s\u1eefa, c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb khu v\u1ef1c \u0110\u1ecba Trung H\u1ea3i v\u00e0 hi\u1ec7n \u0111\u01b0\u1ee3c tr\u1ed3ng r\u1ed9ng r\u00e3i tr\u00ean to\u00e0n th\u1ebf gi\u1edbi nh\u1edd c\u00e1c \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c li\u1ec7u c\u1ee7a n\u00f3. C\u00e1c th\u00e0nh ph\u1ea7n ho\u1ea1t t\u00ednh trong chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 flavonolignan, trong \u0111\u00f3 silymarin l\u00e0 h\u1ee3p ch\u1ea5t n\u1ed5i b\u1eadt nh\u1ea5t v\u00e0 c\u00f3 ho\u1ea1t t\u00ednh sinh h\u1ecdc cao nh\u1ea5t. Silymarin bao g\u1ed3m m\u1ed9t s\u1ed1 flavonolignan, ch\u1ee7 y\u1ebfu l\u00e0 silybin (silibinin), silydianin v\u00e0 silychristin, g\u00f3p ph\u1ea7n t\u1ea1o n\u00ean t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a n\u00f3.<\/span><\/p>\n

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T\u00ednh ch\u1ea5t v\u1eadt l\u00fd v\u00e0 h\u00f3a h\u1ecdc<\/strong><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 d\u1ea1ng b\u1ed9t m\u00e0u n\u00e2u nh\u1ea1t ho\u1eb7c chi\u1ebft xu\u1ea5t kh\u00f4, th\u01b0\u1eddng \u0111\u01b0\u1ee3c chu\u1ea9n h\u00f3a \u0111\u1ec3 ch\u1ee9a m\u1ed9t t\u1ef7 l\u1ec7 ph\u1ea7n tr\u0103m c\u1ee5 th\u1ec3 c\u1ee7a silymarin. V\u1ec1 m\u1eb7t h\u00f3a h\u1ecdc, silymarin l\u00e0 m\u1ed9t h\u1ed7n h\u1ee3p ph\u1ee9c t\u1ea1p c\u1ee7a c\u00e1c flavonolignan, n\u1ed5i b\u1eadt v\u1edbi c\u00e1c \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a v\u00e0 b\u1ea3o v\u1ec7 gan. C\u1ea5u tr\u00fac ph\u00e2n t\u1eed c\u1ee7a silymarin bao g\u1ed3m nhi\u1ec1u nh\u00f3m hydroxyl phenolic, gi\u00fap mang l\u1ea1i ho\u1ea1t t\u00ednh ch\u1ed1ng oxy h\u00f3a th\u00f4ng qua vi\u1ec7c lo\u1ea1i b\u1ecf c\u00e1c g\u1ed1c t\u1ef1 do v\u00e0 \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh peroxy h\u00f3a lipid.<\/span><\/p>\n

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C\u00e1c ngu\u1ed3n t\u1ef1 nhi\u00ean c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa<\/strong><\/span><\/p>\n

Ngu\u1ed3n ch\u00ednh c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 h\u1ea1t c\u1ee7a c\u00e2y k\u1ebf s\u1eefa (*Silybum marianum*), m\u1ed9t lo\u00e0i thu\u1ed9c h\u1ecd C\u00fac (Asteraceae). C\u00e2y n\u00e0y cho ra nh\u1eefng qu\u1ea3 nh\u1ecf, c\u1ee9ng, ch\u1ee9a h\u1ea1t gi\u00e0u flavonolignan c\u00f3 ho\u1ea1t t\u00ednh sinh h\u1ecdc, ch\u1ee7 y\u1ebfu t\u1eadp trung \u1edf v\u1ecf h\u1ea1t. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p chi\u1ebft xu\u1ea5t truy\u1ec1n th\u1ed1ng bao g\u1ed3m vi\u1ec7c nghi\u1ec1n h\u1ea1t v\u00e0 s\u1eed d\u1ee5ng dung m\u00f4i h\u1eefu c\u01a1 \u0111\u1ec3 thu \u0111\u01b0\u1ee3c chi\u1ebft xu\u1ea5t silymarin c\u00f4 \u0111\u1eb7c.<\/span><\/p>\n

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C\u00e1c ph\u01b0\u01a1ng ph\u00e1p chi\u1ebft xu\u1ea5t<\/strong><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa \u0111\u01b0\u1ee3c thu \u0111\u01b0\u1ee3c th\u00f4ng qua c\u00e1c k\u1ef9 thu\u1eadt chi\u1ebft xu\u1ea5t b\u1eb1ng dung m\u00f4i, trong \u0111\u00f3 h\u1ea1t \u0111\u00e3 nghi\u1ec1n n\u00e1t \u0111\u01b0\u1ee3c ng\u00e2m trong dung m\u00f4i nh\u01b0 ethanol ho\u1eb7c methanol \u0111\u1ec3 h\u00f2a tan v\u00e0 chi\u1ebft xu\u1ea5t c\u00e1c h\u1ee3p ch\u1ea5t sinh h\u1ecdc ho\u1ea1t t\u00ednh. C\u00e1c quy tr\u00ecnh tinh ch\u1ebf ti\u1ebfp theo c\u00f3 th\u1ec3 bao g\u1ed3m l\u1ecdc, bay h\u01a1i v\u00e0 s\u1ea5y kh\u00f4 \u0111\u1ec3 t\u1ea1o ra chi\u1ebft xu\u1ea5t chu\u1ea9n h\u00f3a v\u1edbi n\u1ed3ng \u0111\u1ed9 silymarin \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh r\u00f5. Nh\u1eefng ti\u1ebfn b\u1ed9 trong c\u00f4ng ngh\u1ec7 chi\u1ebft xu\u1ea5t \u0111\u00e3 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n cho vi\u1ec7c ph\u00e1t tri\u1ec3n c\u00e1c chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 ho\u1ea1t t\u00ednh cao, ph\u00f9 h\u1ee3p cho c\u00e1c \u1ee9ng d\u1ee5ng trong l\u0129nh v\u1ef1c d\u01b0\u1ee3c ph\u1ea9m v\u00e0 th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng.<\/span><\/p>\n

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\u1ee8ng d\u1ee5ng trong c\u00e1c l\u0129nh v\u1ef1c kh\u00e1c nhau<\/strong><\/span><\/p>\n

B\u1ea3o v\u1ec7 gan v\u00e0 s\u1ee9c kh\u1ecfe gan<\/em><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn r\u1ed9ng r\u00e3i nh\u1edd c\u00e1c \u0111\u1eb7c t\u00ednh b\u1ea3o v\u1ec7 gan, khi\u1ebfn n\u00f3 tr\u1edf th\u00e0nh th\u00e0nh ph\u1ea7n ch\u1ee7 ch\u1ed1t trong c\u00e1c s\u1ea3n ph\u1ea9m b\u1ed5 sung v\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb li\u00ean quan \u0111\u1ebfn s\u1ee9c kh\u1ecfe gan. C\u00e1c h\u1ee3p ch\u1ea5t silymarin gi\u00fap th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh t\u00e1i t\u1ea1o t\u1ebf b\u00e0o gan, \u1ee9c ch\u1ebf c\u00e1c ph\u1ea3n \u1ee9ng vi\u00eam v\u00e0 t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng gi\u1ea3i \u0111\u1ed9c. \u0110i\u1ec1u n\u00e0y khi\u1ebfn chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa tr\u1edf n\u00ean h\u1eefu \u00edch trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh v\u1ec1 gan nh\u01b0 vi\u00eam gan, x\u01a1 gan v\u00e0 gan nhi\u1ec5m m\u1ee1, \u0111\u1ed3ng th\u1eddi h\u1ed7 tr\u1ee3 ch\u1ee9c n\u0103ng gan t\u1ed5ng th\u1ec3 v\u00e0 qu\u00e1 tr\u00ecnh gi\u1ea3i \u0111\u1ed9c.<\/span><\/p>\n

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T\u00e1c d\u1ee5ng ch\u1ed1ng oxy h\u00f3a v\u00e0 ch\u1ed1ng vi\u00eam<\/em><\/span><\/p>\n

C\u00e1c \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa, nh\u1edd v\u00e0o kh\u1ea3 n\u0103ng trung h\u00f2a c\u00e1c g\u1ed1c t\u1ef1 do c\u1ee7a silymarin, g\u00f3p ph\u1ea7n t\u1ea1o n\u00ean t\u00e1c d\u1ee5ng ch\u1ed1ng vi\u00eam c\u1ee7a n\u00f3. B\u1eb1ng c\u00e1ch gi\u1ea3m c\u0103ng th\u1eb3ng oxy h\u00f3a v\u00e0 t\u00ecnh tr\u1ea1ng vi\u00eam, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 th\u1ec3 gi\u00fap l\u00e0m d\u1ecbu c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a c\u00e1c b\u1ec7nh vi\u00eam m\u00e3n t\u00ednh v\u00e0 h\u1ed7 tr\u1ee3 s\u1ee9c kh\u1ecfe t\u1ebf b\u00e0o.<\/span><\/p>\n

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Ki\u1ec3m so\u00e1t cholesterol v\u00e0 \u0111\u01b0\u1eddng huy\u1ebft<\/em><\/span><\/p>\n

C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa, \u0111\u1eb7c bi\u1ec7t l\u00e0 silymarin, c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m n\u1ed3ng \u0111\u1ed9 cholesterol v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ec9 s\u1ed1 lipid b\u1eb1ng c\u00e1ch \u0111i\u1ec1u h\u00f2a qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a lipid v\u00e0 t\u1ed5ng h\u1ee3p axit m\u1eadt. Ngo\u00e0i ra, n\u00f3 c\u00f2n cho th\u1ea5y ti\u1ec1m n\u0103ng trong vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh n\u1ed3ng \u0111\u1ed9 \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 \u0111\u1ed9 nh\u1ea1y insulin, do \u0111\u00f3 mang l\u1ea1i l\u1ee3i \u00edch cho nh\u1eefng ng\u01b0\u1eddi m\u1eafc h\u1ed9i ch\u1ee9ng chuy\u1ec3n h\u00f3a ho\u1eb7c b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng.<\/span><\/p>\n

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Ph\u00f2ng ng\u1eeba ung th\u01b0 v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3<\/em><\/span><\/p>\n

C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 ti\u1ec1m n\u0103ng ch\u1ed1ng ung th\u01b0, ch\u1ee7 y\u1ebfu nh\u1edd kh\u1ea3 n\u0103ng c\u1ee7a silybin trong vi\u1ec7c \u1ee9c ch\u1ebf s\u1ef1 t\u0103ng sinh c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0 v\u00e0 k\u00edch th\u00edch qu\u00e1 tr\u00ecnh apoptosis (ch\u1ebft t\u1ebf b\u00e0o theo ch\u01b0\u01a1ng tr\u00ecnh) \u1edf nhi\u1ec1u lo\u1ea1i ung th\u01b0 kh\u00e1c nhau. M\u1eb7c d\u00f9 c\u1ea7n c\u00f3 th\u00eam c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u1ec3 x\u00e1c th\u1ef1c nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa \u0111\u00f4i khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p b\u1ed5 tr\u1ee3 trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 nh\u1eb1m h\u1ed7 tr\u1ee3 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb truy\u1ec1n th\u1ed1ng v\u00e0 gi\u1ea3m thi\u1ec3u c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 li\u00ean quan \u0111\u1ebfn \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n

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S\u1ee9c kh\u1ecfe da v\u00e0 c\u00e1c \u1ee9ng d\u1ee5ng trong da li\u1ec5u<\/em><\/span><\/p>\n

Nh\u1edd c\u00e1c \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a v\u00e0 ch\u1ed1ng vi\u00eam, c\u00e1c c\u00f4ng th\u1ee9c b\u00f4i ngo\u00e0i da c\u00f3 ch\u1ee9a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c s\u1ea3n ph\u1ea9m ch\u0103m s\u00f3c da. C\u00e1c c\u00f4ng th\u1ee9c n\u00e0y nh\u1eb1m b\u1ea3o v\u1ec7 da kh\u1ecfi t\u00e1c h\u1ea1i t\u1eeb m\u00f4i tr\u01b0\u1eddng, th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh t\u00e1i t\u1ea1o da v\u00e0 l\u00e0m m\u1edd c\u00e1c d\u1ea5u hi\u1ec7u l\u00e3o h\u00f3a nh\u01b0 n\u1ebfp nh\u0103n v\u00e0 \u0111\u1ed1m n\u1eafng.<\/span><\/p>\n

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L\u1ee3i \u00edch s\u1ee9c kh\u1ecfe c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa<\/strong><\/span><\/p>\n

B\u1ea3o v\u1ec7 gan v\u00e0 th\u1ea3i \u0111\u1ed9c<\/em><\/span><\/p>\n

M\u1ed9t trong nh\u1eefng l\u1ee3i \u00edch \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn r\u1ed9ng r\u00e3i nh\u1ea5t c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 kh\u1ea3 n\u0103ng b\u1ea3o v\u1ec7 v\u00e0 h\u1ed7 tr\u1ee3 ch\u1ee9c n\u0103ng gan. C\u00e1c h\u1ee3p ch\u1ea5t silymarin gi\u00fap t\u0103ng c\u01b0\u1eddng qu\u00e1 tr\u00ecnh t\u00e1i t\u1ea1o t\u1ebf b\u00e0o gan, k\u00edch th\u00edch t\u1ed5ng h\u1ee3p protein v\u00e0 th\u00fac \u0111\u1ea9y s\u1ea3n sinh c\u00e1c enzym ch\u1ed1ng oxy h\u00f3a nh\u01b0 glutathione. Nh\u1eefng t\u00e1c d\u1ee5ng n\u00e0y gi\u00fap b\u1ea3o v\u1ec7 t\u1ebf b\u00e0o gan kh\u1ecfi nh\u1eefng t\u1ed5n th\u01b0\u01a1ng do \u0111\u1ed9c t\u1ed1, r\u01b0\u1ee3u, thu\u1ed1c men v\u00e0 stress oxy h\u00f3a g\u00e2y ra.<\/span><\/p>\n

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Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a v\u00e0 kh\u1ea3 n\u0103ng lo\u1ea1i b\u1ecf c\u00e1c g\u1ed1c t\u1ef1 do<\/em><\/span><\/p>\n

Silymarin trong chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng oxy h\u00f3a m\u1ea1nh, c\u00f3 t\u00e1c d\u1ee5ng trung h\u00f2a c\u00e1c g\u1ed1c t\u1ef1 do v\u00e0 c\u00e1c g\u1ed1c oxy ph\u1ea3n \u1ee9ng \u2013 nh\u1eefng y\u1ebfu t\u1ed1 g\u00f3p ph\u1ea7n g\u00e2y t\u1ed5n th\u01b0\u01a1ng t\u1ebf b\u00e0o v\u00e0 qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a. B\u1eb1ng c\u00e1ch t\u0103ng c\u01b0\u1eddng h\u1ec7 th\u1ed1ng ph\u00f2ng v\u1ec7 ch\u1ed1ng oxy h\u00f3a, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 th\u1ec3 gi\u1ea3m c\u0103ng th\u1eb3ng oxy h\u00f3a trong c\u01a1 th\u1ec3, t\u1eeb \u0111\u00f3 h\u1ed7 tr\u1ee3 s\u1ee9c kh\u1ecfe t\u1ed5ng th\u1ec3 v\u00e0 k\u00e9o d\u00e0i tu\u1ed5i th\u1ecd.<\/span><\/p>\n

 <\/p>\n

T\u00ednh ch\u1ea5t ch\u1ed1ng vi\u00eam<\/em><\/span><\/p>\n

Vi\u00eam m\u00e3n t\u00ednh c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn nhi\u1ec1u v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe, bao g\u1ed3m b\u1ec7nh tim m\u1ea1ch, vi\u00eam kh\u1edbp v\u00e0 c\u00e1c r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a. T\u00e1c d\u1ee5ng ch\u1ed1ng vi\u00eam c\u1ee7a silymarin gi\u00fap l\u00e0m gi\u1ea3m c\u00e1c ph\u1ea3n \u1ee9ng vi\u00eam, t\u1eeb \u0111\u00f3 c\u00f3 th\u1ec3 gi\u1ea3m nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh m\u00e3n t\u00ednh v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng mi\u1ec5n d\u1ecbch t\u1ed5ng th\u1ec3.<\/span><\/p>\n

 <\/p>\n

H\u1ed7 tr\u1ee3 ti\u00eau h\u00f3a v\u00e0 l\u01b0u th\u00f4ng m\u1eadt<\/em><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa gi\u00fap c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe h\u1ec7 ti\u00eau h\u00f3a b\u1eb1ng c\u00e1ch k\u00edch th\u00edch s\u1ea3n xu\u1ea5t v\u00e0 l\u01b0u th\u00f4ng m\u1eadt t\u1eeb gan v\u00e0 t\u00fai m\u1eadt. Vi\u1ec7c ti\u1ebft m\u1eadt \u0111\u1ea7y \u0111\u1ee7 l\u00e0 y\u1ebfu t\u1ed1 thi\u1ebft y\u1ebfu cho qu\u00e1 tr\u00ecnh ti\u00eau h\u00f3a ch\u1ea5t b\u00e9o, h\u1ea5p thu d\u01b0\u1ee1ng ch\u1ea5t v\u00e0 th\u1ea3i \u0111\u1ed9c t\u1ed1 ra kh\u1ecfi c\u01a1 th\u1ec3. Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00f3 ti\u00eau, \u0111\u1ea7y b\u1ee5ng v\u00e0 c\u00e1c r\u1ed1i lo\u1ea1n li\u00ean quan \u0111\u1ebfn t\u00fai m\u1eadt nh\u1edd h\u1ed7 tr\u1ee3 qu\u00e1 tr\u00ecnh l\u01b0u th\u00f4ng m\u1eadt.<\/span><\/p>\n

 <\/p>\n

C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra v\u00e0 nh\u1eefng \u0111i\u1ec1u c\u1ea7n l\u01b0u \u00fd<\/strong><\/span><\/p>\n

M\u1eb7c d\u00f9 nh\u00ecn chung \u0111\u01b0\u1ee3c coi l\u00e0 an to\u00e0n cho h\u1ea7u h\u1ebft m\u1ecdi ng\u01b0\u1eddi khi s\u1eed d\u1ee5ng \u0111\u00fang theo h\u01b0\u1edbng d\u1eabn, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00f3 th\u1ec3 g\u00e2y ra m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 nh\u1eb9 \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi, \u0111\u1eb7c bi\u1ec7t l\u00e0 khi d\u00f9ng li\u1ec1u cao ho\u1eb7c s\u1eed d\u1ee5ng trong th\u1eddi gian d\u00e0i. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 g\u1eb7p bao g\u1ed3m:<\/span><\/p>\n

\u2013 R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a: Ch\u1eb3ng h\u1ea1n nh\u01b0 ti\u00eau ch\u1ea3y, kh\u00f3 ch\u1ecbu \u1edf b\u1ee5ng ho\u1eb7c bu\u1ed3n n\u00f4n.<\/span><\/p>\n

\u2013 Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng: C\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng hi\u1ebfm g\u1eb7p, bao g\u1ed3m ph\u00e1t ban da, ng\u1ee9a ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng h\u00f4 h\u1ea5p, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng ng\u01b0\u1eddi nh\u1ea1y c\u1ea3m v\u1edbi c\u00e1c lo\u00e0i th\u1ef1c v\u1eadt thu\u1ed9c h\u1ecd C\u00fac (Asteraceae).<\/span><\/p>\n

Nh\u1eefng ng\u01b0\u1eddi b\u1ecb d\u1ecb \u1ee9ng v\u1edbi c\u1ecf ph\u1ea5n h\u01b0\u01a1ng, hoa c\u00fac, hoa c\u00fac v\u1ea1n th\u1ecd ho\u1eb7c c\u00e1c lo\u00e0i th\u1ef1c v\u1eadt kh\u00e1c thu\u1ed9c h\u1ecd C\u00fac (Asteraceae) n\u00ean th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa ho\u1eb7c ch\u1ec9 d\u00f9ng d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a b\u00e1c s\u0129. Ph\u1ee5 n\u1eef mang thai ho\u1eb7c \u0111ang cho con b\u00fa, c\u0169ng nh\u01b0 nh\u1eefng ng\u01b0\u1eddi c\u00f3 b\u1ec7nh l\u00fd n\u1ec1n ho\u1eb7c \u0111ang d\u00f9ng thu\u1ed1c, n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a chuy\u00ean gia y t\u1ebf tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng c\u00e1c s\u1ea3n ph\u1ea9m b\u1ed5 sung chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa.<\/span><\/p>\n

 <\/p>\n

C\u00e1c kh\u00eda c\u1ea1nh ph\u00e1p l\u00fd v\u00e0 an to\u00e0n<\/strong><\/span><\/p>\n

Chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa \u0111\u01b0\u1ee3c b\u00e1n r\u1ed9ng r\u00e3i d\u01b0\u1edbi d\u1ea1ng th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng, bao g\u1ed3m vi\u00ean nang, vi\u00ean n\u00e9n v\u00e0 chi\u1ebft xu\u1ea5t l\u1ecfng. C\u00e1c c\u01a1 quan qu\u1ea3n l\u00fd nh\u01b0 FDA (C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m) t\u1ea1i Hoa K\u1ef3 v\u00e0 EFSA (C\u01a1 quan An to\u00e0n Th\u1ef1c ph\u1ea9m Ch\u00e2u \u00c2u) t\u1ea1i Ch\u00e2u \u00c2u \u0111\u01b0a ra c\u00e1c h\u01b0\u1edbng d\u1eabn v\u1ec1 an to\u00e0n, ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 ghi nh\u00e3n \u0111\u1ed1i v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa nh\u1eb1m \u0111\u1ea3m b\u1ea3o quy\u1ec1n l\u1ee3i c\u1ee7a ng\u01b0\u1eddi ti\u00eau d\u00f9ng v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a s\u1ea3n ph\u1ea9m.<\/span><\/p>\n

 <\/p>\n

H\u01b0\u1edbng ph\u00e1t tri\u1ec3n v\u00e0 nghi\u00ean c\u1ee9u trong t\u01b0\u01a1ng lai<\/strong><\/span><\/p>\n

C\u00e1c nghi\u00ean c\u1ee9u trong t\u01b0\u01a1ng lai v\u1ec1 chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa nh\u1eb1m m\u1ee5c \u0111\u00edch l\u00e0m s\u00e1ng t\u1ecf th\u00eam v\u1ec1 c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng, ti\u1ec1m n\u0103ng \u0111i\u1ec1u tr\u1ecb v\u00e0 \u1ee9ng d\u1ee5ng c\u1ee7a n\u00f3 trong y h\u1ecdc t\u00edch h\u1ee3p. C\u00e1c l\u0129nh v\u1ef1c tr\u1ecdng t\u00e2m bao g\u1ed3m:<\/span><\/p>\n

\u2013 Th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng: Ti\u1ebfn h\u00e0nh c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf ch\u1eb7t ch\u1ebd nh\u1eb1m \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh v\u1ec1 gan, r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a v\u00e0 c\u00e1c t\u00ecnh tr\u1ea1ng vi\u00eam nhi\u1ec5m.<\/span><\/p>\n

\u2013 Nghi\u00ean c\u1ee9u v\u1ec1 sinh kh\u1ea3 d\u1ee5ng: N\u00e2ng cao sinh kh\u1ea3 d\u1ee5ng c\u1ee7a c\u00e1c h\u1ee3p ch\u1ea5t silymarin th\u00f4ng qua c\u00e1c h\u1ec7 th\u1ed1ng \u0111\u01b0a thu\u1ed1c v\u00e0 k\u1ef9 thu\u1eadt b\u00e0o ch\u1ebf ti\u00ean ti\u1ebfn nh\u1eb1m t\u1ed1i \u01b0u h\u00f3a hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n

\u2013 Nghi\u00ean c\u1ee9u c\u01a1 ch\u1ebf: Nghi\u00ean c\u1ee9u c\u00e1c con \u0111\u01b0\u1eddng ph\u00e2n t\u1eed m\u00e0 qua \u0111\u00f3 silymarin ph\u00e1t huy t\u00e1c d\u1ee5ng ch\u1ed1ng oxy h\u00f3a, ch\u1ed1ng vi\u00eam v\u00e0 b\u1ea3o v\u1ec7 gan nh\u1eb1m x\u00e1c \u0111\u1ecbnh c\u00e1c m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb m\u1edbi.<\/span><\/p>\n

 <\/p>\n

K\u1ebft lu\u1eadn<\/strong><\/span><\/p>\n

T\u00f3m l\u1ea1i, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 m\u1ed9t ph\u01b0\u01a1ng thu\u1ed1c th\u1ea3o d\u01b0\u1ee3c qu\u00fd gi\u00e1 v\u1edbi l\u1ecbch s\u1eed l\u00e2u \u0111\u1eddi trong y h\u1ecdc c\u1ed5 truy\u1ec1n v\u00e0 c\u00e1c \u1ee9ng d\u1ee5ng \u0111i\u1ec1u tr\u1ecb hi\u1ec7n \u0111\u1ea1i. T\u1eeb ngu\u1ed3n g\u1ed1c l\u00e0 m\u1ed9t lo\u1ea1i th\u1ea3o d\u01b0\u1ee3c ch\u1eefa b\u1ec7nh \u1edf khu v\u1ef1c \u0110\u1ecba Trung H\u1ea3i cho \u0111\u1ebfn nh\u1eefng \u1ee9ng d\u1ee5ng hi\u1ec7n nay trong vi\u1ec7c b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe gan, ch\u1ed1ng oxy h\u00f3a v\u00e0 nhi\u1ec1u l\u0129nh v\u1ef1c kh\u00e1c, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa l\u00e0 minh ch\u1ee9ng cho s\u1ef1 t\u01b0\u01a1ng t\u00e1c h\u00e0i h\u00f2a gi\u1eefa c\u00e1c h\u1ee3p ch\u1ea5t t\u1ef1 nhi\u00ean v\u00e0 s\u1ee9c kh\u1ecfe con ng\u01b0\u1eddi. C\u00f9ng v\u1edbi s\u1ef1 ti\u1ebfn b\u1ed9 c\u1ee7a ki\u1ebfn th\u1ee9c khoa h\u1ecdc v\u00e0 nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng, chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa h\u1ee9a h\u1eb9n s\u1ebd g\u00f3p ph\u1ea7n gi\u1ea3i quy\u1ebft nhi\u1ec1u v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe v\u00e0 h\u1ed7 tr\u1ee3 s\u1ee9c kh\u1ecfe t\u1ed5ng th\u1ec3 nh\u1edd c\u00e1c th\u00e0nh ph\u1ea7n sinh h\u1ecdc ho\u1ea1t t\u00ednh m\u1ea1nh m\u1ebd c\u1ee7a n\u00f3.<\/span><\/p>\n

Th\u00f4ng qua vi\u1ec7c nghi\u00ean c\u1ee9u to\u00e0n di\u1ec7n v\u1ec1 chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa \u2014 t\u1eeb th\u00e0nh ph\u1ea7n sinh h\u00f3a \u0111\u1ebfn c\u00e1c \u1ee9ng d\u1ee5ng th\u1ef1c ti\u1ec5n \u2014 ch\u00fang ta c\u00f3 \u0111\u01b0\u1ee3c nh\u1eefng hi\u1ec3u bi\u1ebft qu\u00fd gi\u00e1 v\u1ec1 vai tr\u00f2 c\u1ee7a n\u00f3 nh\u01b0 m\u1ed9t lo\u1ea1i th\u1ea3o d\u01b0\u1ee3c \u0111a n\u0103ng trong c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe t\u1ed5ng h\u1ee3p v\u00e0 b\u1ed5 sung dinh d\u01b0\u1ee1ng. Vi\u1ec7c t\u1eadn d\u1ee5ng nh\u1eefng l\u1ee3i \u00edch c\u1ee7a chi\u1ebft xu\u1ea5t c\u00e2y k\u1ebf s\u1eefa c\u00e0ng kh\u1eb3ng \u0111\u1ecbnh t\u1ea7m quan tr\u1ecdng c\u1ee7a n\u00f3 trong vi\u1ec7c h\u1ed7 tr\u1ee3 ch\u1ee9c n\u0103ng gan, gi\u1ea3m c\u0103ng th\u1eb3ng oxy h\u00f3a, \u0111\u1ed3ng th\u1eddi th\u00fac \u0111\u1ea9y c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn to\u00e0n di\u1ec7n \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe v\u00e0 s\u1ef1 an l\u00e0nh tr\u00ean to\u00e0n th\u1ebf gi\u1edbi.<\/span><\/p>\n

\"\"<\/p>","protected":false},"excerpt":{"rendered":"

Introduction Milk thistle extract, derived from the seeds of the milk thistle plant (*Silybum marianum*), has gained recognition for its […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2074","post","type-post","status-publish","format-standard","hentry","category-press-release"],"_links":{"self":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts\/2074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/comments?post=2074"}],"version-history":[{"count":0,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/posts\/2074\/revisions"}],"wp:attachment":[{"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/media?parent=2074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/categories?post=2074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/collagensei.com\/vi\/wp-json\/wp\/v2\/tags?post=2074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}