L-Carnitine<\/a>?<\/strong><\/span><\/h3>\nTr\u01b0\u1edbc khi \u0111i s\u00e2u v\u00e0o v\u1ea5n \u0111\u1ec1, ch\u00fang ta h\u00e3y l\u00e0m r\u00f5 c\u00e1c h\u1ee3p ch\u1ea5t n\u00e0y l\u00e0 g\u00ec:<\/span><\/p>\n\n- L-Carnitine<\/strong>: M\u1ed9t d\u1eabn xu\u1ea5t axit amin t\u1ef1 nhi\u00ean tham gia v\u00e0o qu\u00e1 tr\u00ecnh v\u1eadn chuy\u1ec3n axit b\u00e9o v\u00e0o ty th\u1ec3, n\u01a1i ch\u00fang \u0111\u01b0\u1ee3c \u0111\u1ed1t ch\u00e1y \u0111\u1ec3 t\u1ea1o ra n\u0103ng l\u01b0\u1ee3ng.<\/span><\/li>\n
- Acetyl L-Carnitine (ALCAR)<\/strong>: M\u1ed9t d\u1ea1ng bi\u1ebfn \u0111\u1ed5i c\u1ee7a L-Carnitine c\u00f3 ch\u1ee9a nh\u00f3m acetyl, gi\u00fap t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng \u0111i qua h\u00e0ng r\u00e0o m\u00e1u-n\u00e3o.<\/span><\/li>\n<\/ul>\n
<\/span>C\u00e1c \u0111\u1eb7c \u0111i\u1ec3m v\u00e0 th\u00f4ng tin c\u01a1 b\u1ea3n<\/strong><\/span><\/span><\/h3>\nH\u00e3y c\u00f9ng ph\u00e2n t\u00edch c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u01a1 b\u1ea3n c\u1ee7a t\u1eebng h\u1ee3p ch\u1ea5t:<\/span><\/p>\n<\/span>L-Carnitine<\/strong><\/span><\/span><\/h4>\n\n- C\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0<\/strong>: Propionyl-L-carnitine<\/span><\/li>\n
- T\u00ean khoa h\u1ecdc<\/strong>: Kh\u00f4ng \u00e1p d\u1ee5ng<\/span><\/li>\n
- S\u1ed1 CAS<\/strong>: 541-15-1<\/span><\/li>\n
- Th\u00f4ng s\u1ed1 k\u1ef9 thu\u1eadt chung<\/strong>: C\u00f3 s\u1eb5n d\u01b0\u1edbi d\u1ea1ng b\u1ed9t, vi\u00ean nang v\u00e0 dung d\u1ecbch (bao g\u1ed3m L-carnitine d\u1ea1ng l\u1ecfng<\/strong>).<\/span><\/li>\n
- H\u00ecnh th\u1ee9c<\/strong>: B\u1ed9t tinh th\u1ec3 m\u00e0u tr\u1eafng.<\/span><\/li>\n
- H\u01b0\u01a1ng v\u1ecb<\/strong>: V\u1ecb ng\u1ecdt nh\u1eb9.<\/span><\/li>\n
- \u0110\u1ed9 h\u00f2a tan<\/strong>: H\u00f2a tan trong n\u01b0\u1edbc.<\/span><\/li>\n
- Li\u1ec1u l\u01b0\u1ee3ng th\u00f4ng th\u01b0\u1eddng<\/strong>: T\u1eeb 500 mg \u0111\u1ebfn 2000 mg m\u1ed7i ng\u00e0y.<\/span><\/li>\n
- L\u01b0u tr\u1eef<\/strong>: B\u1ea3o qu\u1ea3n \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng.<\/span><\/li>\n<\/ul>\n
<\/span>Acetyl L-Carnitine<\/strong><\/span><\/span><\/h4>\n\n- C\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0<\/strong>: ALCAR<\/span><\/li>\n
- T\u00ean khoa h\u1ecdc<\/strong>: Kh\u00f4ng \u00e1p d\u1ee5ng<\/span><\/li>\n
- S\u1ed1 CAS<\/strong>: 505-94-8<\/span><\/li>\n
- Th\u00f4ng s\u1ed1 k\u1ef9 thu\u1eadt chung<\/strong>: C\u00f3 s\u1eb5n \u1edf d\u1ea1ng b\u1ed9t v\u00e0 vi\u00ean nang.<\/span><\/li>\n
- H\u00ecnh th\u1ee9c<\/strong>: B\u1ed9t tinh th\u1ec3 m\u00e0u tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0.<\/span><\/li>\n
- H\u01b0\u01a1ng v\u1ecb<\/strong>: H\u01a1i ng\u1ecdt.<\/span><\/li>\n
- \u0110\u1ed9 h\u00f2a tan<\/strong>: C\u00f3 kh\u1ea3 n\u0103ng h\u00f2a tan trong lipid cao h\u01a1n so v\u1edbi L-Carnitine.<\/span><\/li>\n
- Li\u1ec1u l\u01b0\u1ee3ng th\u00f4ng th\u01b0\u1eddng<\/strong>: Th\u01b0\u1eddng \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb d\u00f9ng t\u1eeb 600 mg \u0111\u1ebfn 2000 mg m\u1ed7i ng\u00e0y.<\/span><\/li>\n
- L\u01b0u tr\u1eef<\/strong>: B\u1ea3o qu\u1ea3n \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, tr\u00e1nh \u1ea9m \u01b0\u1edbt v\u00e0 nhi\u1ec7t \u0111\u1ed9 cao.<\/span><\/li>\n<\/ul>\n
<\/span>B\u1ed1i c\u1ea3nh l\u1ecbch s\u1eed<\/strong><\/span><\/span><\/h3>\nC\u1ea3 hai d\u1ea1ng carnitine n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u trong nhi\u1ec1u th\u1eadp k\u1ef7, ban \u0111\u1ea7u thu h\u00fat s\u1ef1 quan t\u00e2m v\u00e0o nh\u1eefng n\u0103m 1980 v\u00e0 1990 nh\u1edd nh\u1eefng l\u1ee3i \u00edch ti\u1ec1m n\u0103ng \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe. C\u00e1c nghi\u00ean c\u1ee9u ti\u1ebfp t\u1ee5c l\u00e0m s\u00e1ng t\u1ecf c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a ch\u00fang trong vi\u1ec7c t\u0103ng c\u01b0\u1eddng s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng, c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe chuy\u1ec3n h\u00f3a v\u00e0 ch\u1ee9c n\u0103ng nh\u1eadn th\u1ee9c, khi\u1ebfn ch\u00fang tr\u1edf n\u00ean quan tr\u1ecdng trong nhi\u1ec1u \u1ee9ng d\u1ee5ng v\u1ec1 s\u1ee9c kh\u1ecfe v\u00e0 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe ng\u00e0y nay.<\/span><\/p>\n<\/span>So s\u00e1nh hi\u1ec7u qu\u1ea3: L\u1ee3i \u00edch v\u00e0 c\u00f4ng d\u1ee5ng<\/strong><\/span><\/span><\/h3>\nH\u00e3y c\u00f9ng t\u00ecm hi\u1ec3u k\u1ef9 h\u01a1n v\u1ec1 nh\u1eefng l\u1ee3i \u00edch v\u00e0 c\u00f4ng d\u1ee5ng ch\u00ednh c\u1ee7a t\u1eebng h\u1ee3p ch\u1ea5t.<\/span><\/p>\n<\/span>L\u1ee3i \u00edch c\u1ee7a L-Carnitine<\/strong><\/span><\/span><\/h4>\n\n- Chuy\u1ec3n h\u00f3a ch\u1ea5t b\u00e9o<\/strong>: \u0110\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c v\u1eadn chuy\u1ec3n c\u00e1c axit b\u00e9o chu\u1ed7i d\u00e0i v\u00e0o ty th\u1ec3 \u0111\u1ec3 s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng.<\/span><\/li>\n
- Hi\u1ec7u su\u1ea5t t\u1eadp luy\u1ec7n<\/strong>: C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y n\u00f3 c\u00f3 th\u1ec3 gi\u00fap c\u1ea3i thi\u1ec7n s\u1ee9c b\u1ec1n v\u00e0 gi\u1ea3m \u0111au nh\u1ee9c c\u01a1 b\u1eafp sau khi t\u1eadp luy\u1ec7n, khi\u1ebfn n\u00f3 tr\u1edf n\u00ean ph\u1ed5 bi\u1ebfn trong gi\u1edbi v\u1eadn \u0111\u1ed9ng vi\u00ean.<\/span><\/li>\n
- S\u1ee9c kh\u1ecfe tim m\u1ea1ch<\/strong>: T\u00e1c d\u1ee5ng b\u1ea3o v\u1ec7 ti\u1ec1m n\u0103ng \u0111\u1ed1i v\u1edbi ch\u1ee9c n\u0103ng tim v\u00e0 c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111au th\u1eaft ng\u1ef1c.<\/span><\/li>\n<\/ol>\n
<\/span>L\u1ee3i \u00edch c\u1ee7a Acetyl L-Carnitine<\/strong><\/span><\/span><\/h4>\n\n- S\u1ee9c kh\u1ecfe nh\u1eadn th\u1ee9c<\/strong>: \u0110\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi c\u00e1c \u0111\u1eb7c t\u00ednh b\u1ea3o v\u1ec7 th\u1ea7n kinh v\u00e0 kh\u1ea3 n\u0103ng c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng nh\u1eadn th\u1ee9c, gi\u00fap mang l\u1ea1i l\u1ee3i \u00edch trong vi\u1ec7c ng\u0103n ng\u1eeba s\u1ef1 suy gi\u1ea3m nh\u1eadn th\u1ee9c do tu\u1ed5i t\u00e1c.<\/span><\/li>\n
- C\u1ea3i thi\u1ec7n t\u00e2m tr\u1ea1ng<\/strong>: M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u cho th\u1ea5y t\u00e1c \u0111\u1ed9ng t\u00edch c\u1ef1c \u0111\u1ed1i v\u1edbi t\u00e2m tr\u1ea1ng v\u00e0 s\u1ee9c kh\u1ecfe tinh th\u1ea7n, mang l\u1ea1i s\u1ef1 h\u1ed7 tr\u1ee3 cho nh\u1eefng ng\u01b0\u1eddi \u0111ang ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi c\u00e1c tri\u1ec7u ch\u1ee9ng tr\u1ea7m c\u1ea3m.<\/span><\/li>\n
- S\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng<\/strong>: T\u01b0\u01a1ng t\u1ef1 nh\u01b0 L-Carnitine, nh\u01b0ng c\u00f3 th\u00eam l\u1ee3i \u00edch \u0111\u1ed1i v\u1edbi qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a n\u0103ng l\u01b0\u1ee3ng c\u1ee7a n\u00e3o.<\/span><\/li>\n<\/ol>\n
<\/span>Th\u00f4ng tin v\u1ec1 an to\u00e0n<\/strong><\/span><\/span><\/h3>\nC\u1ea3 L-Carnitine v\u00e0 Acetyl L-Carnitine \u0111\u1ec1u \u0111\u01b0\u1ee3c coi l\u00e0 an to\u00e0n khi s\u1eed d\u1ee5ng v\u1edbi li\u1ec1u l\u01b0\u1ee3ng khuy\u1ebfn c\u00e1o. Tuy nhi\u00ean, c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 bao g\u1ed3m:<\/span><\/p>\n\n- L-Carnitine<\/strong>: C\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, bu\u1ed3n n\u00f4n ho\u1eb7c ti\u00eau ch\u1ea3y. Li\u1ec1u cao c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn m\u00f9i c\u01a1 th\u1ec3 tanh do trimethylamine.<\/span><\/li>\n
- Acetyl L-Carnitine<\/strong>: Nh\u00ecn chung, thu\u1ed1c \u0111\u01b0\u1ee3c dung n\u1ea1p t\u1ed1t, tuy nhi\u00ean m\u1ed9t s\u1ed1 ng\u01b0\u1eddi c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 \u0111au \u0111\u1ea7u, b\u1ed3n ch\u1ed3n ho\u1eb7c kh\u00f3 ch\u1ecbu \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/span><\/li>\n<\/ul>\n
C\u00e1c v\u1ea5n \u0111\u1ec1 li\u00ean quan \u0111\u1ebfn quy \u0111\u1ecbnh<\/strong>: C\u1ea3 hai h\u1ee3p ch\u1ea5t n\u00e0y \u0111\u1ec1u \u0111\u01b0\u1ee3c coi l\u00e0 th\u1ef1c ph\u1ea9m b\u1ed5 sung t\u1ea1i Hoa K\u1ef3 v\u00e0 ph\u1ea3i tu\u00e2n th\u1ee7 c\u00e1c quy \u0111\u1ecbnh c\u1ee7a FDA v\u1ec1 ghi nh\u00e3n v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng. C\u00e1c quy \u0111\u1ecbnh t\u01b0\u01a1ng t\u1ef1 c\u0169ng \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng t\u1ea1i ch\u00e2u \u00c2u v\u00e0 c\u00e1c khu v\u1ef1c kh\u00e1c, nh\u1ea5n m\u1ea1nh t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c nh\u1eadp h\u00e0ng t\u1eeb c\u00e1c nh\u00e0 cung c\u1ea5p uy t\u00edn.<\/span><\/p>\n<\/span>Quy tr\u00ecnh s\u1ea3n xu\u1ea5t<\/strong><\/span><\/span><\/h3>\nC\u00e1c quy tr\u00ecnh s\u1ea3n xu\u1ea5t L-Carnitine v\u00e0 Acetyl L-Carnitine c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chi ph\u00ed v\u00e0 t\u00ecnh h\u00ecnh chu\u1ed7i cung \u1ee9ng.<\/span><\/p>\n<\/span>S\u1ea3n xu\u1ea5t L-Carnitine<\/strong><\/span><\/span><\/h4>\n\n- T\u1ed5ng h\u1ee3p<\/strong>: C\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p t\u1eeb lysine v\u00e0 methionine th\u00f4ng qua m\u1ed9t qu\u00e1 tr\u00ecnh h\u00f3a h\u1ecdc g\u1ed3m nhi\u1ec1u b\u01b0\u1edbc.<\/span><\/li>\n
- Chi\u1ebft xu\u1ea5t<\/strong>: Th\u1ec9nh tho\u1ea3ng \u0111\u01b0\u1ee3c chi\u1ebft xu\u1ea5t t\u1eeb ngu\u1ed3n \u0111\u1ed9ng v\u1eadt, m\u1eb7c d\u00f9 c\u00e1c ngu\u1ed3n thu\u1ea7n chay v\u00e0 t\u1ed5ng h\u1ee3p \u0111ang ng\u00e0y c\u00e0ng ph\u1ed5 bi\u1ebfn h\u01a1n.<\/span><\/li>\n
- Qu\u00e1 tr\u00ecnh tinh ch\u1ebf<\/strong>: S\u1ea3n ph\u1ea9m th\u00f4 \u0111\u01b0\u1ee3c \u0111\u01b0a qua qu\u00e1 tr\u00ecnh tinh ch\u1ebf \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 lo\u1ea1i b\u1ecf t\u1ea1p ch\u1ea5t.<\/span><\/li>\n<\/ol>\n
<\/span>S\u1ea3n xu\u1ea5t Acetyl L-Carnitine<\/strong><\/span><\/span><\/h4>\n\n- T\u1ed5ng h\u1ee3p<\/strong>: \u0110\u01b0\u1ee3c t\u1ea1o ra th\u00f4ng qua qu\u00e1 tr\u00ecnh acetyl h\u00f3a L-Carnitine, bao g\u1ed3m vi\u1ec7c th\u00eam m\u1ed9t nh\u00f3m acetyl.<\/span><\/li>\n
- Qu\u00e1 tr\u00ecnh tinh ch\u1ebf<\/strong>: T\u01b0\u01a1ng t\u1ef1 nh\u01b0 L-Carnitine, s\u1ea3n ph\u1ea9m \u0111\u00e3 tr\u1ea3i qua c\u00e1c quy tr\u00ecnh ki\u1ec3m nghi\u1ec7m nghi\u00eam ng\u1eb7t \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o \u0111\u1ed9 tinh khi\u1ebft v\u00e0 hi\u1ec7u qu\u1ea3 cao.<\/span><\/li>\n<\/ol>\n
<\/span>\u1ee8ng d\u1ee5ng tr\u00ean th\u1ecb tr\u01b0\u1eddng<\/strong><\/span><\/span><\/h3>\nC\u1ea3 hai d\u1ea1ng carnitine \u0111\u1ec1u \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i trong c\u00e1c s\u1ea3n ph\u1ea9m b\u1ed5 sung dinh d\u01b0\u1ee1ng v\u00e0 th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng:<\/span><\/p>\n